This article is part of our FanDuel MLB series.
Wednesday's DFS action starts at 6:05 pm EST before giving way to the main slate of games at 7:05 pm EST. There are games at Coors Field and Petco Park as well as options in more neutral parks, so there's plenty to choose from in the player pool.
Pitchers
Dylan Bundy ($9,000) has put together back-to-back quality starts to begin the season and will look keep rolling in Seattle on Wednesday night. Bundy has cut down his home run rate and he continues to strike out over a batter per inning, something he's accomplished in each of the last two seasons. The Mariners have struck out 27 percent of the time this season against right-handed pitchers, the eighth-highest mark in baseball.
Lance McCullers ($8,100) will look to rebound from a rough start and has a good matchup against the Diamondbacks. Arizona has the third-lowest wOBA (.251) against right-handed pitching. Look for him to bounce back in the desert Wednesday night.
A great GPP play for the night is the Rockies' Jon Gray ($6,300). Gray won't be rostered often due to the game being in Colorado, but oddly his career ERA is lower at home (4.34) than on the road (4.52). Gray continues to strike out over a batter per inning and the Giants are merely league average when it comes to team strikeout rate and wOBA. German Marquez put up 53 fantasy points last night against this opponent, and Gray has the same upside.
Top Targets
The Giants' Logan Webb is a good player to target, as he hasn't pitched past the fourth inning in either of his two starts. That means the Rockies should get to San Francisco's second-tier pitching early. All of the Colorado bats are in play but especially Charlie Blackmon ($4,200), who has a career .421 wOBA at home.
Javier Baez ($3,700) qualifies at a position at which it's generally hard to find fantasy production and gets a matchup against a southpaw Wednesday night in rookie Kris Bubic. Bubic isn't considered a top prospect and until this season hadn't pitched above A-ball. Baez has a career .371 wOBA against left-handed pitching and should be able to take advantage.
After a bit of a slow start, Ronald Acuna ($3,700) appears to be hitting his stride and has four straight games of at least 12.5 fantasy points. Acuna had a .374 wOBA against left-handed pitching last season and will get to face Hyun-Jin Ryu on Wednesday night. Look for Acuna to be in his usual leadoff spot and continue his hot run.
Best Values
Todd Frazier ($2,600) offers some salary cap relief along with some upside. He has a career .348 wOBA against lefties and should be hitting cleanup Wednesday night against Sean Manaea. Frazier had one of his best seasons against lefties in 2019, finishing the season with a .382 wOBA in that split.
Lourdes Gurriel ($2,500) might not be an obvious pick, but he's cheap and facing lefty Sean Newcomb. Gurriel has a career .382 wOBA against lefties so he's a logical choice to use in the outfield. He'll make it possible to squeeze in a few bats from Colorado.
Like Acuna, teammate Austin Riley ($2,200) has hit well against left-handed pitching in his short career with the Braves. Riley owns a .346 wOBA against lefties and that number gets inflated to .377 when he's hitting in Atlanta, where he'll be Wednesday night.
Stacks
Cubs vs. Bubic: Baez, Kris Bryant ($3,700), Willson Contreras ($3,000)
All three of these players absolutely rake against lefties, with Bryant owning a career .416 wOBA and Contreras not far behind with a .376 wOBA. Like any rookie, Bubic will experience some bumps in the road, and this matchup looks like one of them. Expect Bryant to get the better of Bubic in the battle of the Krises.
A's vs. Kyle Gibson: Matt Olson ($3,400), Ramon Laureano ($3,300), Khris Davis ($2,500)
It's grabbing the low-hanging fruit to suggest the Rockies or Giants in this area, so I'll look to another team that might not be as popular an option. The Rangers handed Gibson $28 million over three years, which seems like a hefty price for a pitcher coming off a season with a 4.84 ERA supported by a 1.44 WHIP. At this point in his career he has "innings-eater" written all over him. Look for Oakland to take advantage of him Wednesday night. Despite his slow start to the season it's tough to quit Khris Davis, who on any given day can put up a multi-homer effort.