The Latest 49ers Odds For NFL Season 2024
FanDuel 
BetMGM 
BetRivers 
San Francisco 49ers
2-2 (0-1 in the NFC West)
Loading Possible Bets...
49ers Week 5 Matchup
Sunday at 4:05 pm EST
Arizona Cardinals
21.3 Pts
21.3 Pts
@
San Francisco 49ers
28.8 Pts
28.8 Pts
Moneyline
DraftKings Spread
DraftKings Over Under
DraftKings PROBABILITY with vig removed
Cardinals Win (+280)
25.2%
49ers Win (-355)
74.8%
Loading Schedule...
Projected Record: 3-14 (0-6 NFC West)
Win Totals
DraftKings Wins
PROBABILITY with vig removed
Over 10.5 Wins(-125)
52.6%
Under 10.5 Wins(100)
47.4%
LINE MOVEMENT
Super Bowl
DraftKings LINE MOVEMENT
NFC Champ
DraftKings LINE MOVEMENT
NFC West
DraftKings LINE MOVEMENT
49ers Injury Report
Loading 49ers Injuries...
49ers News
DE
Yetur Gross-Matos: Missing Week 5
Oct 4th
Gross-Matos (knee) has been ruled out ahead of Sunday's matchup against the Cardinals, David Lombardi of The San Francisco Standard reports.
LB
Demetrius Flannigan-Fowles: Won't play Sunday
Oct 4th
Flannigan-Fowles (calf) has been ruled out ahead of Sunday's matchup against the Cardinals, David Lombardi of The San Francisco Standard reports.
TE
George Kittle: Listed as questionable
Oct 4th
Kittle (ribs) is listed as questionable for Sunday's game against the Cardinals, Matt Maiocco of NBC Sports Bay Area reports.
TE
George Kittle: Returns to practice
Oct 4th
Kittle (ribs) is practicing Friday, Nick Wagoner of ESPN.com reports.
S
Talanoa Hufanga: Limited in Thursday's practice
Oct 3rd
Hufanga (ankle) was listed as a limited participant on the 49ers' injury report Thursday.
49ers Depth Chart
Quarterback QB
Running Back RB
Wide Receiver WR
- Deebo Samuel
- Brandon Aiyuk
- Jauan Jennings
- Chris Conley Doubt
- Jacob Cowing Ques
- Ronnie Bell
- Ricky Pearsall NFI-R
Tight End TE
Fullback FB