PUP-R
Injury Knee - ACL + MCL
Est. Return 12/22/2025
2025 Receiving Stats
REC
0
YDS
0
TD
0
AVG
0.0
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0
Rest-of-Season Projections
2025 Fantasy Outlook
Aiyuk finally got the big extension he wanted at the end of a contentious 2024 summer, but it wasn't long before the 49ers regretted it. After turning 105 targets into 1,342 yards and seven TDs the year before, Aiyuk had just one game in 2024 with 50-plus yards or double-digit PPR points before suffering ACL and MCL tears Week 7. He had surgery in mid-November, leaving him uncertain for Week 1 of 2025 and unlikely to regain his top form early in the year. Aiyuk will again face tough competition for targets, with Deebo Samuel's offseason departure negated by a breakout 2024 from Jauan Jennings and a strong finish to the year from rookie first-round pick Ricky Pearsall. With TE George Kittle and RB Christian McCaffrey also still kicking, we can probably abandon any prior hopes of Aiyuk seeing a volume spike once Samuel left the 49ers. The good news is that Aiyuk has shown he can put up WR2 fantasy numbers on WR3 volume while serving as the vertical threat in a top offense. However, it's not entirely clear the 49ers still have an elite offense, nor is it certain that Aiyuk will pose the same field-stretching threat a year after major knee surgery. Read Past Outlooks
RANKS
Not ruled out from playing in 2025
San Francisco general manager John Lynch reiterated Tuesday that he's still "hopeful" Aiyuk (knee) will play at some point this season, though Lynch acknowledged that he wasn't sure how realistic the wideout's return might be, Cam Inman of The San Jose Mercury News reports.
ANALYSIS
Lynch noted that Aiyuk is continuing to take part in rehab work for the surgery he underwent last October to address ACL and MCL tears in his right knee, but the 49ers have thus far declined to put out a target date for when the 27-year-old might be ready to practice. As David Lombardi of SFStandard.com suggests, the decision as to whether Aiyuk suits up in 2025 likely falls on the wideout's shoulders. While the 49ers would seemingly welcome him back if he's healthy enough to play, Aiyuk may not be as motivated to suit up after San Francisco voided approximately $26 million in guarantees for the 2026 season back in late July. Aiyuk is still on San Francisco's books through 2028, though the team will likely look to trade him this offseason if it can find a suitor willing to pick up most of his remaining salary. Releasing Aiyuk is another possibility, but the 49ers would incur a dead-cap charge of $29.585 million if he's cut outright without a post-June 1 designation.
Lynch noted that Aiyuk is continuing to take part in rehab work for the surgery he underwent last October to address ACL and MCL tears in his right knee, but the 49ers have thus far declined to put out a target date for when the 27-year-old might be ready to practice. As David Lombardi of SFStandard.com suggests, the decision as to whether Aiyuk suits up in 2025 likely falls on the wideout's shoulders. While the 49ers would seemingly welcome him back if he's healthy enough to play, Aiyuk may not be as motivated to suit up after San Francisco voided approximately $26 million in guarantees for the 2026 season back in late July. Aiyuk is still on San Francisco's books through 2028, though the team will likely look to trade him this offseason if it can find a suitor willing to pick up most of his remaining salary. Releasing Aiyuk is another possibility, but the 49ers would incur a dead-cap charge of $29.585 million if he's cut outright without a post-June 1 designation.
NFL Stats
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Fantasy/Red Zone Stats
See red zone opportunities inside the 20, 10 and 5-yard lines along with the percentage of time they converted the opportunity into a touchdown.
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2025 NFL Game Log
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Snap Distribution / Depth Chart
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Receiving Alignment Breakdown
See where Brandon Aiyuk lined up on the field and how he performed at each spot.
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2025 Brandon Aiyuk Split Stats
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Measurables Review
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How do Brandon Aiyuk's measurables compare to other wide receivers?
This section compares his draft workout metrics with players at the same position. The bar represents the player's percentile rank. For example, if the bar is halfway across, then the player falls into the 50th percentile for that metric and it would be considered average.
Height
6' 0"Weight
200 lbs40-Yard Dash
4.50 secVertical Jump
40.0 inBroad Jump
128 inBench Press
11 repsHand Length
9.75 inArm Length
33.50 inPast Fantasy Outlooks
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Aiyuk and Brock Purdy formed perhaps the most efficient QB/WR duo in the league last season, with 105 passes producing 75 catches (71.4 percent) for 1,342 yards (17.9 YPR, 12.8 YPT) and seven touchdowns. The 2020 first-round pick topped his previous career high for catch rate by three percentage points despite having a sky-high 13.8 aDOT after three straight seasons in the 9.4-9.9 range. That catch rate will be nearly impossible to replicate without the aDOT (and YPR) declining, but Aiyuk still projects as one of the most efficient receivers in the league, catching passes from Purdy in a Kyle Shanahan offense that boasts three other excellent playmakers (Christian McCaffrey, Deebo Samuel and George Kittle). It was Aiyuk who led the group in targets last year, albeit by a small margin with each of the four drawing at least 83 looks. He's now scheduled to play out his age-26 season under the fifth-year option on his rookie contract, presumably hoping to sign an extension this spring/summer (and perhaps considering a holdout if nothing gets done). While no speed demon -- he ran a 4.50 40 at 6-0. 205 pounds in 2020 -- Aiyuk is unusually fluid/quick for someone so stoutly built and tracks balls downfield as naturally as any receiver in the league. He might be a 140-target guy in another offense, but it's hard to imagine him seeing that kind of volume for the Niners unless their other key playmakers have a brutal year for injuries. Of course, he's already shown he doesn't need huge volume to put up strong numbers in such a favorable situation efficiency-wise.
More Fantasy News
Not practicing this week
Aiyuk (knee) won't return to practice this week, Matt Maiocco of NBC Sports Bay Area reports.
ANALYSIS
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Could still play for team in 2025
The 49ers remain committed to getting Aiyuk (knee) "healthy and back on the field" in 2025, even though the team had approximately $27 million in guarantees for the 2026 season voided in his contract, Mike Garafolo of NFL Network reports.
ANALYSIS
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Future with franchise uncertain
Aiyuk (knee) is considered unlikely to play for the 49ers again after the team voided guarantees in his contract for 2026, Dianna Russini and Michael Silver of The Athletic report.
ANALYSIS
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Out for Week 12, still week-to-week
Coach Kyle Shanahan said Monday that Aiyuk's (knee) 21-day practice window will not be opened this week, and he remains week-to-week, Matt Barrows of The Athletic reports.
ANALYSIS
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Unlikely to practice this week
Head coach Kyle Shanahan said Monday that the 49ers don't intend to open Aiyuk's (knee) practice window this week, Nick Wagoner of ESPN.com reports.
ANALYSIS
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Latest Fantasy Rumors
Grim outlook on return
General manager John Lynch said he is hoping Aiyuk will play at some point this season during an interview on 680 KNBR on Tuesday.
ANALYSIS
The comment on its own isn't particularly alarming, but Lynch was asked if he had a realistic belief Aiyuk will play this season. Lynch responded that he wasn't sure if there was a realistic chance, but instead that he was hoping for Aiyuk's return. There's plenty of drama following Aiyuk this season, as it was previously reported that he would not play again for the 49ers and that appears to be a potential outcome.
The comment on its own isn't particularly alarming, but Lynch was asked if he had a realistic belief Aiyuk will play this season. Lynch responded that he wasn't sure if there was a realistic chance, but instead that he was hoping for Aiyuk's return. There's plenty of drama following Aiyuk this season, as it was previously reported that he would not play again for the 49ers and that appears to be a potential outcome.







