Top MLB Betting Picks for September 16: Expert Predictions and Best Bets
Previous article 0-1 ( -1.00 units) (Dodgers/Giants picks were voided as Logan Webb did not start)
Season 132-138-2 (-10.05 units)
Cash in on the best sportsbook promos available at the best MLB betting sites this baseball season. The BetMGM bonus code gets new players one of the best welcome bonuses in the industry.
Key MLB Betting Trends and Matchups Analysis
Before locking in your MLB bets Tuesday, be sure to check out these key betting numbers.
As teams fall out of the playoff race, we will start to see inflated moneylines.
Road Favorites - Braves -190 at Nationals
Home Favorites - Brewers -255 vs Angels
Totals - Marlins/Rockies 10.0-10.5, Braves/Nationals 7.0, Cubs/Pirates 7.0-7.5
Line Movement - Guardians -51, Yankees -26,
Guardians/Tigers 7.0 to 8.0
Check out Caesars' MLB offerings this season using the Caesars Sportsbook promo code at signup for a generous welcome offer.
Chicago Cubs vs Pittsburgh Pirates Best Bets and Predictions
I have been doing this all season and no reason to stop now. We are going to bank on Paul Skenes not allowing a run in the first three innings. Cade Horton on the other side for the Cubs has been impressive and should win the NL Rookie of the Year.
Both starting pitchers have ERA's sub 1.60 in their last 7 starts. Horton has a 1.24 ERA in his last 7 starts with just 2 homeruns allowed along with a 36:7 K:BB ratio. The Cubs are averaging 4.0 runs per game in their last 10 and the Pirates are at just 2.8 runs per game over their last 10.
As I writing this article on Monday night, I had locked in the total of 7.5 to the UNDER and sure enough the line already moved to 6.5-7.0. This one will most likely get to 6.5 across the board, so grab it quickly if you can find a 7.0.
Best Bet: Cubs UNDER 0.5 runs for 1 unit (DraftKings ); Cubs/Pirates UNDER 7.0 runs for 1 unit (Caesars -109)
Check in on one of the top sports betting apps when you sign up with the bet365 bonus code for your baseball betting.
Baltimore Orioles vs Chicago White Sox Best Bets and Predictions
It is not often that you find the White Sox as home favorites (first time in 2025), but they deserve it here with Shane Smith pitching against Dean Kremer. Smith has actually gotten the win in 3 out of his last 4 starts, which says a lot pitching for the White Sox. Kremer has not pitched terribly, but he got walloped in two starts against the Giants and Astros, which have blown up his overall stats. Kremer is also returning to the mound after having his last start skipped due to forearm discomfort.
The White Sox are just 3 games under .500 since the All-Star Break (25-28).
Best Bet: White Sox ML for 1 unit (FanDuel -130)
Sports betting is officially live in the state of Massachusetts. To get the most bang for your buck when selecting a sportsbook as a new customer, check out these Massachusetts Sports Betting Promos.
Tuesday's MLB Best Bets
- Cubs UNDER 0.5 runs for 1 unit (DraftKings )
- Cubs/Pirates UNDER 7.0 runs for 1 unit (Caesars -109)
- White Sox ML for 1 unit (FanDuel -130)
- BONUS PICK - Phillies ML for 1 unit (BetRivers +100). Love getting Cristopher Sanchez at EVEN money against the Dodgers who are still not playing great and the Phillies are heating up again.
- BONUS PICK - Padres ML for 1 unit () I can not get behind the Mets at all right now.