This article is part of our Soccer Picks series.
Note this article will be updated throughout the week with any corresponding news. To see all projected and confirmed lineups on one page, please click here.
Last update: 3:15 p.m. EDT on Friday, Oct. 16
MATCHES (EDT)
- Saturday, 7:30 am: Everton vs. Liverpool
- Saturday, 10:00 am: Chelsea vs. Southampton
- Saturday, 12:30 pm: Manchester City vs. Arsenal
- Saturday, 3:00 pm: Newcastle United vs. Manchester United
- Sunday, 7:00 am: Sheffield United vs. Fulham
- Sunday, 9:00 am: Crystal Palace vs. Brighton & Hove Albion
- Sunday, 11:30 am: Tottenham Hotspur vs. West Ham United
- Sunday, 2:15 pm: Leicester City vs. Aston Villa
- Monday, 12:30 pm: West Bromwich Albion vs. Burnley
- Monday, 3:00 pm: Leeds United vs. Wolverhampton
Arsenal (at Manchester City)
Out: Calum Chambers (knee), Pablo Mari (ankle), Gabriel Martinelli (knee), Shkodran Mustafi (hamstring)
Questionable: Pierre-Emerick Aubameyang (ankle), Sokratis (calf), Emile Smith-Rowe (shoulder), Kieran Tierney (COVID-19 related)
Previous Lineup (4-3-3 in 2-1 win v. Sheffield United): Bernd Leno (GK), Hector Bellerin (DR), Gabriel (DC), David Luiz (DC), Kieran Tierney (DL), Mohamed Elneny (MC), Bukayo Saka (MC), Dani Ceballos (MC), Willian (FWR), Pierre-Emerick Aubameyang (FWL), Edward Nketiah (FW)
Projected Lineup (3-4-3 v. Manchester City): Bernd Leno (GK), Rob Holding (DC), Gabriel (DC), David Luiz (DC), Hector Bellerin (MR), Bukayo Saka (ML), Thomas Partey (MC), Dani Ceballos (MC), Willian (FWR), Pierre-Emerick Aubameyang (FWL), Alexandre Lacazette (FW)
Notes: Arsenal move for more defensive help, adding Holding to the back line and immediately installing Thomas in central midfield. Ceballos could be preferred to Granit Xhaka alongside Thomas, while Lacazette moves back in to replace Nketiah up top.
Aston Villa (at Leicester City)
Out: Tom Heaton (knee), Wesley Moraes (knee), Bjorn Engels (thigh)
Questionable: Kortney Hause (knock)
Previous Lineup (4-2-3-1 in 7-2 win v. Liverpool): Emiliano Martinez (GK), Matty Cash (DR), Tyrone Mings (DC), Ezri Konsa (DC), Matt Targett (DL), John McGinn (DMC), Douglas Luiz (DMC), Trezeguet (AMR), Ross Barkley (AMC), Jack Grealish (AML), Ollie Watkins (FW)
Projected Lineup (4-2-3-1 v. Leicester City): Emiliano Martinez (GK), Matty Cash (DR), Tyrone Mings (DC), Ezri Konsa (DC), Matt Targett (DL), John McGinn (DMC), Douglas Luiz (DMC), Trezeguet (AMR), Ross Barkley (AMC), Jack Grealish (AML), Ollie Watkins (FW)
Notes: After the thrashing of Liverpool, Villa have no reason to change the XI. The lone switch could be Bertrand Traore replacing Trezeguet on the wing or Marvelous Nakamba for Luiz, who returns from international duty.
Brighton (at Crystal Palace)
Out: Florin Andone (knee), Jose Izquierdo (knee), Alireza Jahanbakhsh (hamstring), Christian Walton (ankle)
Questionable: Tariq Lamptey (hamstring), Davy Propper (Achilles)
Previous Lineup (3-4-2-1 in 4-2 loss at Everton): Mathew Ryan (GK), Lewis Dunk (DC), Ben White (DC), Adam Webster (D), Tariq Lamptey (MR), Yves Bissouma (MC), Steven Alzate (MC), Solomon March (ML), Neal Maupay (AMC), Leandro Trossard (AMC), Aaron Connolly (FW)
Projected Lineup (3-4-3 v. Crystal Palace) : Mathew Ryan (GK), Lewis Dunk (DC), Ben White (DC), Adam Webster (D), Tariq Lamptey (MR), Yves Bissouma (MC), Steven Alzate (MC), Solomon March (ML), Neal Maupay (FWL), Leandro Trossard (FWR), Aaron Connolly (FW)
Notes: Lamptey should be ready after getting two weeks to recover a minor hamstring injury, while everyone else stays the same. Adam Lallana could take the spot of Connolly after the latter featured for Ireland over the break.
Burnley (at West Brom)
Out: Robbie Brady (ribs), Jack Cork (ankle), Matthew Lowton (knock), Ben Mee (thigh)
Questionable: Kevin Long (eye), Jay Rodriguez (ankle), Johann Berg Gudmundsson (groin)
Previous Lineup (4-4-2 in 3-1 loss at Newcastle): Nick Pope (GK), Phil Bardsley (DR), Kevin Long (DC), James Tarkowski (DC), Charlie Taylor (DL), Josh Brownhill (MR), Ashley Westwood (MC), Dale Stephens (MC), Dwight McNeil (ML), Chris Wood (FW), Ashley Barnes (FW)
Projected Lineup (4-4-2 v. West Brom): Nick Pope (GK), Phil Bardsley (DR), Kevin Long (DC), James Tarkowski (DC), Charlie Taylor (DL), Josh Brownhill (MR), Ashley Westwood (MC), Dale Stephens (MC), Dwight McNeil (ML), Chris Wood (FW), Ashley Barnes (FW)
Notes: Long may miss out after injuring his eye over the break, which means Jimmy Dunne would return to the XI. There's also a chance Gudmundsson features again, possibly for Stephens or Brownhill, after recovering prior to the break.
Chelsea (v. Southampton)
Out: Edouard Mendy (thigh), Thiago Silva (rest), Billy Gilmour (knee)
Questionable: Ben Chilwell (foot), Hakim Ziyech (knee)
Previous Lineup (4-2-3-1 in 4-0 win v. Crystal Palace): Edouard Mendy (GK), Cesar Azpilicueta (DR), Thiago Silva (DC), Kurt Zouma (DC), Ben Chilwell (DL), Jorginho (DMC), N'Golo Kante (DMC), Callum Hudson-Odoi (AMR), Kai Havertz (AMC), Timo Werner (AML), Tammy Abraham (FW)
Projected Lineup (4-2-3-1 v. Southampton): Kepa Arrizabalaga (GK), Ben Chilwell (DL), Andreas Christensen (DC), Kurt Zouma (DC), Reece James (DR), Jorginho (DMC), N'Golo Kante (DMC), Christian Pulisic (AMR), Kai Havertz (AMC), Timo Werner (AML), Tammy Abraham (FW)
Notes: Pulisic slots back into the starting XI now that he's fully fit, while Kepa comes in for the injured Mendy. Elsewhere, Christensen starts for Thiago, who is being rested after returning from international duty.
Crystal Palace (v. Brighton)
Out: Nathan Ferguson (knee), James McCarthy (knock), Connor Wickham (undisclosed), Wayne Hennessey (knock)
Questionable: Gary Cahill (hamstring), James Tomkins (hamstring), Patrick van Aanholt (shoulder), Jeffrey Schlupp (strain)
Previous Lineup (4-4-2 in 4-0 loss at Chelsea): Vicente Guaita (GK), Joel Ward (DR), Mamadou Sakho (DC), Cheikhou Kouyate (DC), Tyrick Mitchell (DL), Andros Townsend (MR), James McArthur (MC), James McCarthy (MC), Eberechi Eze (ML), Jordan Ayew (FW), Wilfried Zaha (FW)
Projected Lineup (4-4-2 v. Brighton): Vicente Guaita (GK), Joel Ward (DR), Mamadou Sakho (DC), Cheikhou Kouyate (DC), Tyrick Mitchell (DL), Andros Townsend (MR), James McArthur (MC), Luka Milivojevic (MC), Eberechi Eze (ML), Jordan Ayew (FW), Wilfried Zaha (FW)
Notes: Milivojevic is set for his first start of the season after McCarthy returned from the break with an injury. Elsewhere, Patrick van Aanholt is edging closer and Nathaniel Clyne could eventually feature, and the same goes for Michy Batshuayi or Christian Benteke up front.
Everton (v. Liverpool)
Out: Jean-Philippe Gbamin (Achilles), Mason Holgate (toe), Jonjoe Kenny (ankle), Jarrad Branthwaite (ankle), Cenk Tosun (knee)
Questionable: Seamus Coleman (hamstring), Richarlison (ankle), Andre Gomes (knock), Allan (Groin), Yerry Mina (thigh), Lucas Digne (knee)
Previous Lineup (4-3-3 in 4-2 win v. Brighton): Jordan Pickford (GK), Seamus Coleman (DR), Michael Keane (DC), Yerry Mina (DC), Lucas Digne (DL), Abdoulaye Doucoure (MC), Tom Davies (MC), Gylfi Sigurdsson (MC), James Rodriguez (FWR), Richarlison (FWL), Dominic Calvert-Lewin (FW)
Projected Lineup (4-3-3 v. Liverpool): Jordan Pickford (GK), Seamus Coleman (DR), Michael Keane (DC), Yerry Mina (DC), Lucas Digne (DL), Abdoulaye Doucoure (MC), Allan (MC), Andre Gomes (MC), James Rodriguez (FWR), Richarlison (FWL), Dominic Calvert-Lewin (FW)
Notes: Mina starts after recovering from his thigh injury, while Allan and Gomes reclaim their spots in the starting XI after being held out against Brighton due to injuries, moving Davies and Sigurdsson to the bench.
Fulham (at Sheffield United)
Out: Kenny Tete (calf), Harrison Reed (knock), Joachim Andersen (ankle)
Questionable: Mario Lemina (knock)
Previous Lineup (4-2-3-1 in 1-0 loss at Wolverhampton): Alphonse Areola (GK), Ola Aina (DR), Maxime Le Marchand (DC), Tim Ream (DC), Antonee Robinson (DL), Tom Cairney (DMC), Andre Zambo Anguissa (DMC), Ivan Cavaleiro (AMR), Bobby Decordova-Reid (AMC), Joe Bryan (AML), Aleksandar Mitrovic (FW)
Projected Lineup (4-2-3-1 v. Sheffield United): Alphonse Areola (GK), Ola Aina (DR), Maxime Le Marchand (DC), Tim Ream (DC), Joe Bryan (DL), Ruben Loftus-Cheek (DMC), Andre Zambo Anguissa (DMC), Ivan Cavaleiro (AMR), Bobby Decordova-Reid (AMC), Ademola Lookman (AML), Aleksandar Mitrovic (FW)
Notes: Lookman takes over on the left wing, shifting Bryan to left-back, while Ream starts for the injured Andersen and Loftus-Cheek replaces Cairney in the midfield.
Leeds United (v. Wolves)
Out: Diego Llorente (groin)
Questionable: Liam Cooper (groin), Adam Forshaw (hip), Pablo Hernandez (groin)
Previous Lineup (4-1-4-1 in 1-1 draw v. Manchester City): Illan Meslier (GK), Luke Ayling (DR), Liam Cooper (DC), Robin Koch (DC), Stuart Dallas (DL), Kalvin Phillips (DMC), Helder Costa (MR), Mateusz Klich (MC), Tyler Roberts (MC), Ezgjan Alioski (ML), Patrick Bamford (FW)
Projected Lineup (4-1-4-1 v. Wolves): Illan Meslier (GK), Luke Ayling (DR), Pascal Struijk (DC), Robin Koch (DC), Stuart Dallas (DL), Kalvin Phillips (DMC), Helder Costa (MR), Mateusz Klich (MC), Tyler Roberts (MC), Jack Harrison (ML), Patrick Bamford (FW)
Notes: Harrison replaces Alioski after sitting out against parent club Manchester City, and Struijk takes over for the injured Cooper at center-back.
Leicester City (v. Aston Villa)
Out: Wilfred Ndidi (groin), Ricardo Pereira (knee), Caglar Soyuncu (thigh), Filip Benkovic (hip), Daniel Amartey (hamstring)
Questionable: Jamie Vardy (calf), Demarai Gray (illness), James Maddison (calf), Dennis Praet (knee), Jonny Evans (abdomen), Wes Morgan (back)
Previous Lineup (3-4-3 in 0-3 loss v. West Ham): Kasper Schmeichel (GK), Jonny Evans (DC), Caglar Soyuncu (DC), Daniel Amartey (DC), Timothy Castagne (MR), Youri Tielemans (MC), Nampalys Mendy (MC), James Justin (ML), Ayoze Perez (FWR), Harvey Barnes (FWL), Jamie Vardy (FW)
Projected Lineup (4-3-3 v. Aston Villa): Kasper Schmeichel (GK), Timothy Castagne (DR), Jonny Evans (DC), Wesley Fofana (DC), James Justin (DL), Nampalys Mendy (MC), Youri Tielemans (MC), Dennis Praet (MC), Ayoze Perez (FWR), Harvey Barnes (FWL), Jamie Vardy (FW)
Notes: Praet returns from injury to reclaim his spot in the starting XI, while Leicester revert to a back-four, including a debut for Fofana.
Liverpool (at Everton)
Out: Alisson Becker (shoulder), Naby Keita (COVID-19), Alex Oxlade-Chamberlain (knee), Konstantinos Tsimikas (thigh)
Questionable: Thiago Alcantara (COVID-19), Sadio Mane (COVID-19), Joel Matip (muscular strain)
Previous Lineup (4-3-3 in 7-2 loss at Aston Villa): Adrian (GK), Trent Alexander-Arnold (DR), Virgil van Dijk (DC), Joe Gomez (DC), Andrew Robertson (DL), Fabinho (MC), Georginio Wijnaldum (MC), Naby Keita (MC), Mohamed Salah (FWR), Diogo Jota (FWL), Roberto Firmino (FW)
Projected Lineup (4-3-3 at Everton): Adrian (GK), Trent Alexander-Arnold (DR), Virgil van Dijk (DC), Joe Gomez (DC), Andrew Robertson (DL), Thiago Alcantara (MC), Georginio Wijnaldum (MC), Jordan Henderson (MC), Mohamed Salah (FWR), Sadio Mane (FWL), Roberto Firmino (FW)
Notes: Mane returns after recovering from COVID-19 to reclaim his spot up front, pushing Jota to the bench, while Henderson and Thiago replace Keita and Fabinho.
Manchester City (v. Arsenal)
Out: Gabriel Jesus (strain), Kevin De Bruyne (leg), Adrian Bernabe (lower leg)
Questionable: Sergio Aguero (knee), Ilkay Gundogan (COVID-19), Raheem Sterling (hamstring), Oleksandr Zinchenko (strain)
Previous Lineup (4-3-3 in 1-1 draw at Leeds United): Ederson (GK), Benjamin Mendy (DL), Ruben Dias (DC), Aymeric Laporte (DC), Kyle Walker (DR), Kevin De Bruyne (MC), Phil Foden (MC), Rodri (MC), Ferran Torres (FWR), Raheem Sterling (FWL), Riyad Mahrez (FW)
Projected Lineup (4-3-3 v. Arsenal): Ederson (GK), Benjamin Mendy (DL), Ruben Dias (DC), Aymeric Laporte (DC), Kyle Walker (DR), Phil Foden (MC), Ilkay Gundogan (MC), Rodri (MC), Ferran Torres (FWR), Raheem Sterling (FWL), Riyad Mahrez (FW)
Notes: Gundogan is back from COVID-19, replacing an injured De Bruyne in the XI. Foden moves back into the midfield while Torres keeps his spot on the wing and Mahrez centrally in place of Aguero, who is only fit enough for the bench.
Manchester United (at Newcastle)
Out: Anthony Martial (suspension), Edinson Cavani (COVID-19 related), Axel Tuanzebe (foot), Phil Jones (undisclosed)
Questionable: Harry Maguire (knock), Alex Telles (rest), Daniel James (illness)
Previous Lineup (4-2-3-1 in 1-6 loss to Tottenham): David de Gea (GK), Aaron Wan-Bissaka (DR), Harry Maguire (DC), Eric Bailly (DC), Luke Shaw (DL), Paul Pogba (DMC), Nemanja Matic (DMC), Mason Greenwood (AMR), Bruno Fernandes (AMC), Marcus Rashford (AML), Anthony Martial (FW)
Projected Lineup (4-3-1-2 v. Newcastle): David de Gea (GK), Aaron Wan-Bissaka (DR), Victor Lindelof (DC), Eric Bailly (DC), Luke Shaw (DL), Nemanja Matic (MC), Paul Pogba (MC), Donny van de Beek (MC), Bruno Fernandes (AMC), Mason Greenwood (FW), Marcus Rashford (FW)
Notes: van de Beek enters for the suspended Martial, which changes the formation, leaving Greenwood and Rashford as the top forwards. Additionally, Lindelof comes back in for Maguire, who stays on the bench due to a knock.
Newcastle (v. Manchester United)
Out: Martin Dubravka (heel), Dwight Gayle (knee), Matt Ritchie (shoulder), Matthew Longstaff (thigh), Paul Dummett (knock), Ciaran Clark (thigh)
Questionable: Jamaal Lascelles (knock), Jamal Lewis (Achilles), Allan Saint-Maximin (ankle), DeAndre Yedlin (knock)
Previous Lineup (4-4-2 in 3-1 win v. Burnley): Karl Darlow (GK), Emil Krafth (DR), Federico Fernandez (DC), Fabian Schar (DC), Jamal Lewis (DL), Jeff Hendrick (MR), Isaac Hayden (MC), Jonjo Shelvey (MC), Allan Saint-Maximin (ML), Callum Wilson (FW), Joelinton (FW)
Projected Lineup (4-4-2 v. Manchester United) : Karl Darlow (GK), Javier Manquillo (DR), Federico Fernandez (DC), Fabian Schar (DC), Jamal Lewis (DL), Jeff Hendrick (MR), Isaac Hayden (MC), Jonjo Shelvey (MC), Allan Saint-Maximin (ML), Callum Wilson (FW), Joelinton (FW)
Notes: Manquillo returns to the XI, moving Krafth back to the bench, while Lascelles' return takes Schar out of the lineup.
Sheffield United (v. Fulham)
Out: Jack O'Connell (knee), Lys Mousset (toe)
Questionable: Oliver Burke (knock), John Egan (COVID-19 related), David McGoldrick (hip), John Fleck (back)
Previous Lineup (3-5-2 in 2-1 loss at Arsenal): Aaron Ramsdale (GK), John Egan (DC), Jack Robinson (DC), Chris Basham (DC), George Baldock (MR), Sander Berge (MC), John Lundstram (MC), Ben Osborn (MC), Enda Stevens (ML), David McGoldrick (FW), Oliver Burke (FW)
Projected Lineup (3-5-2 v. Fulham) : Aaron Ramsdale (GK), Ethan Ampadu (DC), Jack Robinson (DC), Chris Basham (DC), George Baldock (MR), Sander Berge (MC), John Lundstram (MC), Ben Osborn (MC), Enda Stevens (ML), Rhian Brewster (FW), Oliver Burke (FW)
Notes: Ampadu returns to the XI after Egan came in close contact with a COVID-19 positive player. Brewster makes his debut for the injured McGoldrick.
Southampton (at Chelsea)
Out: Stuart Armstrong (COVID-19), Moussa Djenepo (hamstring)
Questionable: none
Previous Lineup (4-4-2 in 2-0 win v. West Brom): Alex McCarthy (GK), Kyle Walker-Peters (DR), Jan Bednarek (DC), Jannik Vestergaard (DC), Ryan Bertrand (DL), Stuart Armstrong (MR), Oriol Romeu (MC), James Ward-Prowse (MC), Moussa Djenepo (ML), Che Adams (FW), Danny Ings (FW)
Projected Lineup (4-4-2 v. Chelsea): Alex McCarthy (GK), Kyle Walker-Peters (DR), Jan Bednarek (DC), Jannik Vestergaard (DC), Ryan Bertrand (DL), Nathan Redmond (MR), Oriol Romeu (MC), James Ward-Prowse (MC), Theo Walcott (ML), Che Adams (FW), Danny Ings (FW)
Notes: Redmond is back from injury, while Theo Walcott steps in for Armstrong, who tested positive for COVID-19.
Tottenham (v. West Ham)
Out: Giovani Lo Celso (thigh), Japhet Tanganga (thigh)
Questionable: Gareth Bale (knee), Eric Dier (hamstring)
Previous Lineup (4-3-3 in 1-6 win at Manchester United): Hugo Lloris (GK), Serge Aurier (DR), Eric Dier (DC), Davinson Sanchez (DC), Sergio Reguilon (DL), Pierre-Emile Hojbjerg (MC), Moussa Sissoko (MC), Tanguy Ndombele (MC), Erik Lamela (FWR), Son Heung-Min (FWL), Harry Kane (FW)
Projected Lineup (4-3-3 v. West Ham): Hugo Lloris (GK), Matt Doherty (DR), Toby Alderweireld (DC), Davinson Sanchez (DC), Sergio Reguilon (DL), Pierre-Emile Hojbjerg (MC), Tanguy Ndombele (MC), Harry Winks (MC), Lucas Moura (AMR), Son Heung-Min (AML), Harry Kane (FW)
Notes: Doherty returns to replace Aurier at right-back, while Lucas Moura starts for Lamela up front and Alderweireld comes in for the banged up Dier. Winks also returns in place of Lo Celso.
West Brom (at Burnley)
Out: Hal Robson-Kanu (arm)
Questionable: Ahmed Hegazi (hamstring), Callum Robinson (COVID-19 related)
Previous Lineup (4-2-3-1 in 2-0 loss at Southampton): Sam Johnstone (GK), Dara O'Shea (DR), Semi Ajayi (DC), Kyle Bartley (DC), Conor Townsend (DL), Jake Livermore (DMC), Romaine Sawyers (DMC), Kyle Edwards (AMR), Matheus Pereira (AMC), Grady Diangana (AML), Callum Robinson (FW)
Projected Lineup (5-4-1 v. Burnley): Sam Johnstone (GK), Dara O'Shea (DR), Semi Ajayi (DC), Kyle Bartley (DC), Branislav Ivanovic (DC), Kieran Gibbs (DL), Jake Livermore (MC), Romaine Sawyers (MC), Matheus Pereira (MR), Grady Diangana (ML), Karlan Grant (FW)
Notes: Gibbs returns from suspension to push Townsend to the bench, while Krovinovic starts in the midfield after coming off the bench last match. Grant could get his first start after signing with the club Thursday, though Robinson is possible if he gets COVID clearance.
West Ham (at Tottenham)
Out: None
Questionable: Issa Diop (illness), Ryan Fredericks (hamstring), Arthur Masuaku (knee)
Previous Lineup (5-4-1 in 0-3 win at Leicester City): Lukasz Fabianski (GK), Vladimir Coufal (DR), Aaron Cresswell (DC), Angelo Ogbonna (DC), Fabian Balbuena (DC), Arthur Masuaku (DL), Jarrod Bowen (MR), Declan Rice (MC), Tomas Soucek (MC), Pablo Fornals (ML), Michail Antonio (FW)
Projected Lineup (5-4-1 v. Tottenham): Lukasz Fabianski (GK), Ryan Fredericks (DR), Aaron Cresswell (DC), Angelo Ogbonna (DC), Fabian Balbuena (DC), Arthur Masuaku (DL), Jarrod Bowen (MR), Declan Rice (MC), Tomas Soucek (MC), Pablo Fornals (ML), Michail Antonio (FW)
Notes: West Ham continue with what's working as long as Masuaku is healthy, though Fredericks could come back in for Coufal. Diop is also an option for Balbuena or Ogbonna.
Wolverhampton (at Leeds)
Out: Jonny (knee)
Questionable: Fernando Marcal (calf)
Previous Lineup (3-5-2 in 1-0 win v. Fulham): Rui Patricio (GK), Willy Boly (DC), Conor Coady (DC), Max Kilman (DC), Nelson Semedo (MR), Pedro Neto (MC), Leander Dendoncker (MC), Ruben Neves (MC), Romain Saiss (ML), Daniel Podence (FW), Raul Jimenez (FW)
Projected Lineup (3-4-3 v. Leeds): Rui Patricio (GK), Willy Boly (DC), Conor Coady (DC), Romain Saiss (DC), Nelson Semedo (MR), Joao Moutinho (MC), Ruben Neves (MC), Fernando Marcal (ML), Daniel Podence (FWR), Pedro Neto (FWL), Raul Jimenez (FW)
Notes: Wolves return to a 3-4-3 with Marcal returning to the left wing, replacing Kilman in the XI. Moutinho is also back in the midfield in place of Dendoncker. Traore continues to be the odd man out, though he could start for Podence or Marcal.
