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Ty Chandler
Chance to be RB1 after bye
Chandler could be atop Minnesota's running back depth chart in Week 7 against the Lions, as Kevin Seifert of ESPN.com reports that Jones was ruled out of Sunday's 23-17 win over the Jets due to a hip injury.
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Raheem Mostert
Could step up with Achane concussed
Mostert could be in line to take over atop Miami's running back depth chart, as De'Von Achane suffered a concussion in Sunday's 15-10 win over the Patriots.
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Derrick Henry
Milestones on horizon
Jeff Zrebiec of The Athletic believes Henry could be in for big performance Sunday against a Bengals' defense that ranks 25th against the run this season.
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Jordan Mason
Starter through Week 6
With Christian McCaffrey not expected to return from injured reserve when eligible for Week 6 against the Seahawks, Mason will continue to serve as the 49ers' starting running back, Adam Schefter of ESPN reports.
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Brian Robinson
Game-time decision Week 5
Robinson is listed as questionable due to a knee injury and is projected to be a game-time decision for Sunday's Week 5 matchup against the Browns, John Keim of ESPN.com reports.
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Austin Ekeler
Could be top back Sunday
Ekeler, who missed the Week 4 win over the Cardinals with a concussion, is off the injury report and could function as the top back in a Week 5 matchup against the Browns due to Brian Robinson's knee injury, John Keim of ESPN.com reports.
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Trey Sermon
Getting starting nod Sunday
Sermon is officially expected to serve as the Colts' No. 1 running back in Sunday's Week 5 matchup against the Jaguars due to Jonathan Taylor being sidelined due to an ankle injury, Stephen Holder of ESPN.com reports.
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Jonathan Taylor
Sitting out Week 5
Taylor will not play in Sunday's game against the Jaguars due to an ankle injury, Stephen Holder of ESPN.com reports.
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Alexander Mattison
Chance for lead role Week 5
Mattison could be poised to lead Vegas' backfield against the Broncos in Week 5, as Zamir White purportedly suffered a groin injury in practice Wednesday, Paul Gutierrez of ESPN.com reports.
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Cam Akers
Still in starting mix
Akers has a chance to log a third consecutive start in Week 5 against the Bills, as Aaron Wilson of KPRC 2 Houston reports that Joe Mixon didn't practice Wednesday due to an ankle injury.
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Kenneth Walker
Big workload expected
Walker should become the bell cow back for Seattle in the coming weeks, Brady Henderson of ESPN reports.
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Keaton Mitchell
Still on track for November return
Mitchell is nearing a return to practice, Adam Schefter of ESPN reports.
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Jonathan Taylor
Likely avoids serious injury
Taylor was diagnosed with a mild high-ankle sprain following Sunday's win over the Steelers, and he may not miss any time, Ian Rapoport of NFL Network reports.
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Nick Chubb
Moving toward season debut
Chubb is expected to begin practicing Wednesday, which would open his 21-day window for activation from the PUP list as he completes his recovery from knee surgery, Ian Rapoport of NFL Network reports.
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Aaron Shampklin
Could move up to RB2 in Week 5
Shampklin could play a meaningful role in Week 5 against the Cowboys, as Dale Lolley of the Steelers' official site reports that Cordarrelle Patterson left Sunday's 27-24 loss to the Colts due to an ankle injury.
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Trey Sermon
Next in line if Taylor misses time
Sermon could take on a larger role in Week 5 against the Jaguars, as James Boyd of The Athletic reports that Jonathan Taylor suffered an ankle injury in Sunday's 27-24 win over the Steelers.
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Jeremy McNichols
Will back up Robinson on Sunday
With Austin Ekeler ruled out ahead of Sunday's game against the Cardinals due to a concussion, McNichols is set to serve as the Commanders' No. 2 running back behind Brian Robinson, John Keim of ESPN.com reports.
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Sean Tucker
Could be thrust into larger role
Tucker may see a significant uptick in offensive snaps due to both Rachaad White and Bucky Irving being listed as questionable for Sunday's game against the Eagles, Scott Smith of the Buccaneers' official site reports.
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Jamaal Williams
Bigger workload in Week 4?
Williams could see a larger snap count on offense Sunday against the Falcons due to lead running back Alvin Kamara dealing with hip and rib injuries, John Sigler of USA Today reports.
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Cordarrelle Patterson
Could step into Warren's role
Patterson's in line for an increased role in Week 4 against the Colts, as Alan Saunders of SteelersNow.com reports that Jaylen Warren missed a second consecutive practice Thursday due to a knee injury.
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Cam Akers
Trending toward another start
Akers is well positioned to start again in Week 4 against the Jaguars, as Joe Mixon and Dameon Pierce both remained sidelined at practice Thursday, DJ Bien-Aime of ESPN.com reports.
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Tyler Allgeier
Bijan banged up?
Bijan Robinson was limited at Thursday's practice due to a shoulder injury, per Tori McElhaney of the Falcons' official site, and Allgeier would be in line for a larger role Sunday against the Saints if Robinson's out or limited.
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Aaron Jones
Looking forward to Lambeau return
Jones is excited about potentially taking a Lambeau Leap against his old Packers squad during Sunday's game in Green Bay, Kevin Seifert of ESPN.com reports.
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Carson Steele
Getting veteran backfield mate
Steele will be joined in the Chiefs backfield by veteran Kareem Hunt for Sunday's matchup against the Chargers after the latter was signed off the practice squad Wednesday, Adam Teicher of ESPN.com reports.
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Kareem Hunt
Signed to active roster
Hunt was officially added to the Chiefs' active roster from the practice squad Wednesday, Adam Teicher of ESPN.com reports.
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