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Spencer BurfordFull participant in practice
OGSan Francisco 49ers
Knee
October 29, 2025
Burford (knee) was a full participant in San Francisco's practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
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Jake BrendelSits out practice
CSan Francisco 49ers
Hamstring
October 29, 2025
Brendel (hamstring) didn't participate in San Francisco's practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
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Ben BartchLimited in practice
OGSan Francisco 49ers
Ankle
October 29, 2025
Bartch (ankle) was a limited participant in San Francisco's practice Wednesday, David Lombardi of SFStandard.com reports.
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Jordan ElliottLimited participant in practice
DTSan Francisco 49ers
Ankle
October 29, 2025
Elliott (ankle) was a limited participant in San Francisco's practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
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Sam OkuayinonuCan't practice Wednesday
DESan Francisco 49ers
Ankle
October 29, 2025
Okuayinonu (ankle) did not participate at practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
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Bryce HuffStill sidelined with hamstring
DESan Francisco 49ers
Hamstring
October 29, 2025
Huff (hamstring) did not participate at practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
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Upton StoutDealing with shoulder issue
CBSan Francisco 49ers
Shoulder
October 29, 2025
Stout (shoulder) was a limited participant at practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
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Dee WintersDoesn't practice Wednesday
LBSan Francisco 49ers
Knee
October 29, 2025
Winters (knee) did not participate at practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
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Mac JonesFull practice Wednesday
QBSan Francisco 49ers
October 29, 2025
Jones (knees) practiced in full Wednesday, Eric Branch of the San Francisco Chronicle reports.
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Brock PurdyRemains limited in practice
QBSan Francisco 49ers
Toe
October 29, 2025
Purdy (toe) officially was limited at Wednesday's practice, Eric Branch of the San Francisco Chronicle reports.
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Ricky PearsallNot practicing yet
WRSan Francisco 49ers
Knee - PCL
October 29, 2025
Pearsall (knee) isn't practicing Wednesday, Vic Tafur of The Athletic reports.
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Brock PurdyIn line for limited practice
QBSan Francisco 49ers
Toe
October 29, 2025
Coach Kyle Shanahan said Purdy (toe) is expected to be limited at Wednesday's practice, Nick Wagoner of ESPN.com reports.
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Jake TongesScores, but plays just five snaps
TESan Francisco 49ers
October 29, 2025
Tonges recorded a two-yard touchdown reception on his lone target while playing five of the 49ers' 48 snaps on offense in Sunday's 26-15 loss to the Texans.
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Jordan WatkinsOne catch in NFL debut
WRSan Francisco 49ers
October 29, 2025
Watkins recorded a seven-yard reception on two targets in Sunday's 26-15 loss to the Texans.
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Isaac GuerendoNo run on offense this season
RBSan Francisco 49ers
October 29, 2025
Guerendo played all 10 of his snaps on special teams in Sunday's 26-15 loss to the Texans.
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Malik MustaphaSeason-high stops in Week 8 loss
SSan Francisco 49ers
October 28, 2025
Mustapha made 12 tackles (six solo) during Sunday's loss to the Texans.
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Tatum BethuneLogs double-digit stops again
LBSan Francisco 49ers
October 28, 2025
Bethune made 14 tackles (four solo) during Sunday's loss to the Texans.
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Keion WhiteSent to Bay Area
LBSan Francisco 49ers
October 28, 2025
The 49ers acquired White and a 2026 seventh-round pick from the Patriots on Tuesday in exchange for a 2026 sixth-round pick, Tom Pelissero of NFL Network reports.
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Dee WintersLabeled day-to-day
LBSan Francisco 49ers
Knee
October 27, 2025
Head coach Kyle Shanahan said Monday that Winters is considered day-to-day due to a knee injury he sustained during Sunday's 26-15 loss to the Texans, Jennifer Lee Chan of NBC Sports Bay Area reports.
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Brandon AiyukUnlikely to have practice window opened this week
WRSan Francisco 49ers
Knee - ACL + MCL
October 27, 2025
Coach Kyle Shanahan said Monday that the 49ers don't intend to designate Aiyuk (knee) to return from the reserve/PUP list Wednesday, Matt Barrows of The Athletic reports.
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Mac JonesDay-to-day due to knee contusion
QBSan Francisco 49ers
Knee
October 27, 2025
Coach Kyle Shanahan said Monday that Jones suffered a bruised knee during Sunday's 26-15 loss at Houston and is "day-to-day," David Lombardi of SFStandard.com reports.
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Brock PurdyMay return in Week 9
QBSan Francisco 49ers
Toe
October 27, 2025
Purdy (toe) has a chance to return to action Sunday at the Giants, Nick Wagoner of ESPN.com reports. "It's too early to say," coach Kyle Shanahan said Monday. "I don't think it's a long shot. We'll see how he's doing on Wednesday."
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Skyy MooreSplits snaps between offense and ST
WRSan Francisco 49ers
October 27, 2025
Moore failed to collect his only target on offense while returning two kicks for 52 yards in Sunday's 26-15 loss to the Texans.
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Demarcus RobinsonConverts two-point attempt Sunday
WRSan Francisco 49ers
October 27, 2025
Robinson pulled in two of three targets for five yards while catching a successful two-point attempt in Sunday's 26-15 loss to Houston.
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Brian RobinsonLimited to two offensive snaps
RBSan Francisco 49ers
October 27, 2025
Robinson did not record a touch on offense while returning three kicks for 99 yards in Sunday's 26-15 loss to the Texans.
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