Even on the road, Josh Allen and the Bills are 2.5-point favorites over the Super Bowl champion Rams to kick off the season.
Jeff Erickson attempts to help you resolve your start/sit dilemmas with his Week 1 Rankings.
Get the latest fantasy football rankings with RotoWire's top 150 players in PPR formats. Find out which players are sliding up and down draft boards.
The Titans are Jerry Donabedian's top streamer for Week 1, but he also likes Myles Garrett and the Browns as a multi-week option thanks to a favorable early schedule.
Jeff Stotts advises that although both are healthy now, Cam Akers and Matthew Stafford have the types of injuries that can linger throughout the season.
Kevin Payne analyzes the top waiver-wire options for Week 1, including Mitch Trubisky, who was named the starter in Pittsburgh.
Michael Rathburn gives an early read on some notable line movements heading into NFL Week 1. Visit RotoWire for more NFL betting picks and analysis all season long.
Alan Seslowsky loves sneaking 49ers Jeff Wilson onto his rosters when he can.
Jim Coventry analyzes a wide receiver ADP battle between Tyreek Hill, Mike Evans and Tee Higgins. Who you got?
Dan Marcus analyzes the risers and fallers in football as the season nears. Can Chris Godwin really make it back for Week 1?
Alan Seslowsky insists Jalen Hurts is the correct answer at QB in 2022.
In the third and final top-150 Roundtable Rankings, Dameon Pierce took a huge leap among the RotoWire football writers. Find out who else moved up or down.
Mike Doria reviews his NFFC Classic draft, including the decision to go with Mark Andrews in the second round.
Dameon Pierce's ascent continues, fueled by Marlon Mack's recent demotion to the practice squad.
Jim Coventry recaps Wednesday's preseason news as Darren Waller returned to practice for the Raiders.
Sony Michel was a surprising cut by the Dolphins, but he might soon crash another coveted RB role rather than fade into obscurity.
Michael Gallup might not be ready for Week 1, but Week 2 or 3 isn't out of the question. He avoided the PUP list, while Bills CB Tre'Davious White was less fortunate.
Kevin Payne analyzes the top waiver options for the last week of preseason, including the Titans' Malik Willis.