This article is part of our FanDuel Fantasy Football series.
Welcome to my weekly FanDuel strategy piece. Over the season, we will cover a variety of topics - from tournament strategy to player ownership and, of course, matchups to exploit each and every week. The goal will be to prepare you with an array of tools to help build optimal lineups. This week we will break down each game on the schedule, looking for matchups to exploit and players to target based on their opponents' weaknesses.
Bills at Jaguars (Bills -5)
Matchup: Defensive, low-scoring; 42 O/U
Key Stats: Jaguars 3.4 YPC allowed; Bills 25th ranked defense vs WR
Players: Allen Robinson; Bills D/ST
Buccaneers at Redskins (Redskins -3.5)
Matchup: Two sub-par defenses; 43 O/U
Key Stats: Bucs 20th ranked defense vs QB; Redskins allowed 221 rush yards last week
Players: Doug Martin; Kirk Cousins
Falcons at Titans (Falcons -4)
Matchup: Two sub-par defenses; 48 O/U
Key Stats: Titans 18th ranked defense vs QB; Falcons 32nd ranked defense vs RB
Players: Matt Ryan; Julio Jones; Devonta Freeman
Saints at Colts (Colts -4.5)
Matchup: Offensive; High-scoring; 52.5 O/U
Key Stats: Saints 31st ranked defense vs QB; Colts 24th ranked defense vs QB
Players: Andrew Luck; Donte Moncrief; Drew Brees
Vikings at Lions (Vikings -2.5)
Matchup: Divisional battle; potentially high-scoring; 44.5 O/U
Key Stats: Lions 25th ranked defense vs RB; Vikings fourth ranked defense vs QB
Players: Adrian Peterson; Calvin Johnson
Steelers at Chiefs (Steelers -3.5)
Matchup: Two sub-par pass defenses; 45 O/U
Key Stats: Chiefs 32nd ranked defense vs WR; Steelers 29th ranked defense vs TE
Players: Antonio Brown; Travis Kelce
Browns at Rams (Rams -5.5)
Matchup: defensive; low-scoring; 42 O/U
Key Stats: Browns 27th ranked defense vs RB; Rams third ranked defense vs QB
Players: Todd Gurley; Rams D/ST
Texans at Dolphins (Dolphins -4.5)
Matchup: two sub-par defenses; potentially high-scoring; 44.5 O/U
Key Stats: Dolphins 22nd ranked defense vs WR; Texans 26th ranked defense vs QB
Players: DeAndre Hopkins; Ryan Tannehill; Jarvis Landry
Jets at Patriots (Patriots -9)
Matchup: defensive; potential blowout; 48.5 O/U
Key Stats: Jets 2nd ranked defense vs QB and vs RB; Patriots 26th ranked defense vs WR
Players: Rob Gronkowski; Brandon Marshall
Raiders at Chargers (Chargers -4)
Matchup: two sub-par defenses; high-scoring; 47 O/U
Key Stats: Raiders 32nd ranked defense vs TE; Chargers 31st ranked defense vs RB
Players: Latavius Murray; Philip Rivers; Antonio Gates
Cowboys at Giants (Giants -3.5)
Matchup: two struggling offenses; 45.5 O/U
Key Stats: Cowboys 15th ranked defense vs QB; Giants 23th ranked defense vs RB
Players: Odell Beckham Jr.; Joseph Randle
Eagles at Panthers (Panthers -4)
Matchup: NFC battle; potentially high-scoring; 46 O/U
Key Stats: Eagles 14th ranked defense vs QB; Panthers 22nd ranked defense vs RB
Players: Cam Newton; Greg Olsen; DeMarco Murray
Ravens at Cardinals (Cardinals -7.5)
Matchup: potential blowout; high-scoring; 48.5 O/U
Key Stats: Ravens 32nd ranked defense vs QB; Cardinals 9th ranked defense vs QB
Players: Carson Palmer; Larry Fitzgerald; Cardinals D/ST