This article is part of our MLB Picks series.
MLB Bets Today: Free MLB Picks for Wednesday, September 21
RotoWire.com's Michael Rathburn has dug into the best sports betting sites across the country to identify his MLB bets and MLB player props to target today.
Last Article's Record: 2-1 +1.00 units
Season Record:185-165-5 +33.16 units
Arizona Diamondbacks 
at Los Angeles Dodgers 
Whenever you have a -300 home favorite, the automatic lean is look at -1.5 and what the odds are. In this case, we get under the -140 threshold and avoid a -2.5 run line as well. It also helps when you have a very bad pitcher on the other side in Madison Bumgarner. MadBum has really struggled recently and against the Dodgers. He has an 8.35 ERA in his last seven starts and 6.85 in his last five against the Dodgers.
MLB Best Bets for Diamondbacks at Dodgers
- Dodgers -1.5 runs for 1.38 RW buck (DraftKings -138)
- Dodgers over 5.5 runs for 1 RW buck (DraftKings -105)
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Houston Astros 
at Tampa Bay Rays 
I passed on the total for the Rays/Astros yesterday because of the line move from 7 to 6 and it still ended up going under, but just barely. The Rays have been held scoreless by the Astros pitching staff in the last two games. Lance McCullers has a 2.43 ERA in his last seven starts and probably allows 2 earned runs in this game which he has done in his last 3 starts. The hope is the Astros bullpen shuts down the Rays' offense for the remaining part of the game.
MLB Best Bets for Astros at Rays
- Rays UNDER 3.5 runs for 1.40 RW buck (DraftKings -140)
Chicago Cubs 
at Miami Marlins 
The Marlins UNDER paid off again as they scored just 1 run yesterday in a 2-1 loss to the Cubs. This is a similar situation as yesterday with Marcus Stroman going for the Cubs. He has only allowed 2 home runs in his last 7 starts with a 2.90 ERA. Because the threat of a homerun is diminished in the park, the opposing pitcher, and heck the Marlins bats, I'm going UNDER on their team total again.
MLB Best Bets for Cubs at Marlins
- Marlins UNDER 3.5 runs for 1.35 RW buck (DraftKings -135)
Los Angeles Angels 
at Texas Rangers 
One of my system plays is when we have two suspect starting pitchers, it warrants a heavy look at the OVER for the game and we get that here with Tucker Davidson against Dane Dunning. Both have an ERA in the 6.00 range in their last seven starts. Both teams are averaging close to 4.0 runs per game in the month of September. That is against "average" so we get the below average in this game which has a 6-5 type of feel to it.
MLB Best Bets for Angels at Rangers
- Angels/Rangers OVER 8.5 runs for 1.08 RW buck (FanDuel -108)
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MLB Best Bets Today Recap
- Dodgers -1.5 runs for 1.38 RW buck (DraftKings -138)
- Dodgers OVER 5.5 runs for 1 RW buck (DraftKings -105)
- Rays UNDER 3.5 runs for 1.40 RW buck (DraftKings -140)
- Marlins UNDER 3.5 runs for 1.35 RW buck (DraftKings -135)
- Angels/Rangers OVER 8.5 runs for 1.08 RW buck (FanDuel -108)
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Visit RotoWire all season long for exclusive sports betting picks from our group of handicappers with their expert MLB picks each day of the campaign. Remember that betting apps vary in terms of odds and available MLB player props, so we have an easy-to-use MLB odds page that allows you to shop for the best lines at DraftKings, FanDuel, BetMGM and PointsBet.
Before you place your bets, be sure to use all of RotoWire's MLB resources, like our MLB Lineups page, MLB Weather page, and the best batter vs. pitcher stats.
