Despite hosting Arsenal at the Etihad, Manchester City are solid favorites, which means plenty of fantasy managers will be looking to stack the Citizens.
Barcelona are the biggest favorites on Saturday's five-game interleague slate, which means plenty of fantasy managers will be looking at Lionel Messi.
There aren't expected to be many goals during Saturday's five-game slate, which means many fantasy players could be paying up for Mohamed Salah.
Andrew Laird and Mike Gottlieb preview the upcoming weekend of Premier League matches, which includes a number of dangerous revenge games, though none as bloodthirsty as Jose Mourinho bringing his Manchester United squad to Stamford Bridge.
James Milner has been a dominant fantasy option of late, but is his rising price worth it Saturday against West Ham?
Mohamed Salah has four goals in his last four matches in all competitions, and he'll look to extend his streak of fine play Saturday at West Ham.
Tottenham's home match against Crystal Palace will get plenty of people looking to give the fantasy captain's armband to striker Harry Kane.
Andrew Laird and Jordan Cooper preview Saturday's daily fantasy Premier League slate, including some strategies for DraftKings' Pick'Em contests and whether it's necessary to stack Liverpool away to West Ham.
With the top five teams in the table playing Sunday, fantasy players could be looking to stack Liverpool as they face off against West Ham at London Stadium.
With Arsenal away to Manchester City and Chelsea hosting Manchester United, many fantasy managers could turn toward Christian Eriksen, who will get to face Crystal Palace at Wembley Stadium.
After a disappointing 1-1 draw in Cyprus two weeks ago, Borussia Dortmund are expected to come out swinging at home against Apoel Nicosia on Wednesday.
Andrew Laird and Tom Devine preview Wednesday's seven-game fantasy Champions League slate, including which Liverpool players should be targeted (hint: all of them) and how to navigate the Spurs-Real Madrid and Napoli-Man City clashes.
Liverpool are big favorites at home against Maribor on Wednesday, and their attacking group is likely to get plenty of attention from fantasy players.
Atletico Madrid need a big performance out of Antoine Griezmann against Qarabag on Tuesday if they want to have a realistic shot at advancing to the group stage.
Despite possibly being without Philippe Coutinho, Liverpool are the biggest favorites on Wednesday's Champions League slate, and Mohamed Salah could have a major impact.
Paris Saint-Germain's home match against Anderlecht will have plenty of fantasy players targeting Neymar, who returns after serving a one-match domestic ban.
Andrew Laird and Jordan Cooper review this past weekend's daily fantasy Premier League slate, including how much Manchester City exposure they had, and then preview Tuesday's eight-game Champions League slate.