This article is part of our Soccer Picks series.
Note this article will be updated throughout the week with any corresponding news. To see all projected and confirmed lineups on one page, please click here.
Last update: 10:30 a.m. EDT on Fri., Nov. 6
MATCHES (EST)
- Friday, 12:30 pm: Brighton & Hove Albion vs. Burnley
- Friday, 3:00 pm: Southampton vs. Newcastle United
- Saturday, 7:30 am: Everton vs. Manchester United
- Saturday, 10:00 am: Crystal Palace vs. Leeds United
- Saturday, 12:30 pm: Chelsea vs. Sheffield United
- Saturday, 3:00 pm: West Ham United vs. Fulham
- Sunday, 7:00 am: West Bromwich Albion vs. Tottenham Hotspur
- Sunday, 9:00 am: Leicester City vs. Wolverhampton
- Sunday, 11:30 am: Manchester City vs. Liverpool
- Sunday, 2:15 pm: Arsenal vs. Aston Villa
Arsenal v. Aston Villa
- Previous Result: 0-1 win at Manchester United (Sunday)
- Out: Pablo Mari (ankle), Gabriel Martinelli (knee), Calum Chambers (knee), Reiss Nelson (out)
- Questionable:
- Previous Europa League Lineup (Thurs., Nov. 5): Bernd Leno (GK), Sead Kolasinac (DL), David Luiz (DC), Shkodran Mustafi (DC), Ainsley Maitland-Niles (DR), Dani Ceballos (DMC), Granit Xhaka (DMC), Joe Willock (AMC), Nicolas Pepe (AWL), Willian (AWR), Edward Nketiah (FW)
- Projected Lineup (4-3-3 v. Aston Villa): Bernd Leno (GK), Kieran Tierney (DL), David Luiz (DC), Gabriel (DC), Hector Bellerin (DR), Mohamed Elneny (MC), Bukayo Saka (MC), Thomas Partey (MC), Pierre-Emerick Aubameyang (FWL), Willian (FWR), Alexandre Lacazette (FW)
- Notes: Arsenal keep things similar to last week with Luiz returning to the starting XI over Rob Holding.
Aston Villa at Arsenal
- Previous Result: 3-4 loss v. Southampton (Sunday)
- Out: Kortney Hause (groin), Tom Heaton (knee), Wesley Moraes (knee), Bertrand Traore (groin)
- Questionable:
- Projected Lineup (4-2-3-1 v. Arsenal): Emiliano Martinez (GK), Matt Targett (DL), Tyrone Mings (DC), Ezri Konsa (DC), Matty Cash (DR), Douglas Luiz (DMC), John McGinn (DMC), Jack Grealish (AML), Ross Barkley (AMC), Trezeguet (AMR), Ollie Watkins (FW)
- Notes: An injury to Traore moves Trezeguet back into the XI.
Brighton & Hove Albion v. Burnley
- Previous Result: 2-1 loss at Tottenham (Sunday)
- Out: Lewis Dunk (suspension), Jose Izquierdo (knee), Florin Andone (knee), Christian Walton (ankle)
- Questionable: Solomon March (ankle), Alireza Jahanbakhsh (hamstring), Tariq Lamptey (cramp)
- Projected Lineup (3-4-2-1 v. Burnley): Mathew Ryan (GK), Ben White (DC), Joel Veltman (DC), Adam Webster (DC), Bernardo (ML), Yves Bissouma (MC), Steven Alzate (MC), Tariq Lamptey (MR), Adam Lallana (AMC), Leandro Trossard (AMC), Neal Maupay (FW)
- Notes: Maupay returns after a one-match absence, while March miss out, moving Bernardo, Gross or even Alexis Mac Allister into the XI.
Burnley at Brighton & Hove Albion
- Previous Result: 0-3 loss v. Chelsea (Saturday)
- Out: Jack Cork (ankle), Erik Pieters (calf)
- Questionable: Ben Mee (thigh), Phil Bardsley (COVID-19), Johann Berg Gudmundsson (calf)
- Projected Lineup (4-4-2 v. Brighton): Nick Pope (GK), Matthew Lowton (DR), Ben Mee (DC), James Tarkowski (DC), Charlie Taylor (DL), Josh Brownhill (MR), Dale Stephens (MC), Ashley Westwood (MC), Dwight McNeil (ML), Chris Wood (FW), Ashley Barnes (FW)
- Notes: Mee makes an immediate return to the starting XI with Burnley in need of points, pushing Kevin Long to the bench, while Bardsley could take the spot of Lowton, and Gudmundsson is an outside chance.
Chelsea v. Sheffield United
- Previous Result: 0-3 win at Burnley (Saturday), 3-0 win v. Rennes (Wednesday)
- Out: Billy Gilmour (shoulder), Kai Havertz (COVID-19)
- Questionable: Christian Pulisic (hamstring), Kepa Arrizabalaga (shoulder)
- Previous Champions League Lineup (Wed., Nov. 4): Edouard Mendy (GK), Ben Chilwell (DL), Thiago Silva (DC), Kurt Zouma (DC), Reece James (DR), N'Golo Kante (MC), Jorginho (MC), Mason Mount (MC), Hakim Ziyech (FWR), Tammy Abraham (FW), Timo Werner (FWL)
- Projected Lineup (4-3-3 v. Sheffield United): Edouard Mendy (GK), Ben Chilwell (DL), Thiago Silva (DC), Kurt Zouma (DC), Cesar Azpilicueta (DR), N'Golo Kante (MC), Jorginho (MC), Mason Mount (MC), Hakim Ziyech (FWR), Tammy Abraham (FW), Timo Werner (FWL)
- Notes: Chelsea use what worked midweek unless Frank Lampard decides to give Callum Hudson-Odoi a rare start, while Azpilicueta gives Reece James rest at right-back.
Crystal Palace v. Leeds United
- Previous Result: 2-0 loss at Wolverhampton (Saturday)
- Out: Luka Milivojevic (suspension), Nathan Ferguson (knee), Wayne Hennessey (undisclosed), Connor Wickham (undisclosed), Joel Ward (undisclosed), Tyrick Mitchell (knock), James Tomkins (thigh)
- Questionable: Jack Butland (illness), Gary Cahill (shin), James McCarthy (thigh)
- Projected Lineup (4-4-2 v. Leeds United): Vicente Guaita (GK), Patrick van Aanholt (DL), Gary Cahill (DC), Cheikhou Kouyate (DC), Nathaniel Clyne (DR), Jeffrey Schlupp (ML), James McArthur (MC), Jairo Riedewald (MC), Andros Townsend (MR), Wilfried Zaha (FW), Michy Batshuayi (FW)
- Notes: It's more of the same for Palace outside a return for Cahill at center-back, and McArthur starts for the suspended Milivojevic.
Everton v. Manchester United
- Previous Result: 2-1 loss at Newcastle United (Sunday)
- Out: Richarlison (suspension), Jean-Philippe Gbamin (Achilles), Mason Holgate (toe)
- Questionable: Andre Gomes (knee), Seamus Coleman (hamstring), James Rodriguez (undisclosed), Ben Godfrey (hamstring)
- Projected Lineup (4-3-3 v. Manchester United): Jordan Pickford (GK), Lucas Digne (DL), Michael Keane (DC), Yerry Mina (DC), Seamus Coleman (DR), Andre Gomes (MC), Allan (MC), Abdoulaye Doucoure (MC), James Rodriguez (FWR), Dominic Calvert-Lewin (FW), Gylfi Sigurdsson (FWL)
- Notes: Digne returns from suspension and Coleman is back from a hamstring injury. James also comes back in, moving Everton to a 4-3-3 again.
Fulham at West Ham United
- Previous Result: 2-0 win v. West Bromwich Albion (Monday)
- Out: Aboubakar Kamara (suspension), Terence Kongolo (foot), Kenny Tete (calf)
- Questionable: Mario Lemina (undisclosed), Neeskens Kebano (undisclosed)
- Projected Lineup (4-2-3-1 v. West Ham): Alphonse Areola (GK), Joachim Andersen (DC), Ola Aina (DR), Tosin Adarabioyo (DC), Antonee Robinson (DL), Tom Cairney (AMC), Andre Zambo Anguissa (DMC), Harrison Reed (DMC), Ademola Lookman (AML), Bobby Decordova-Reid (AMR), Aleksandar Mitrovic (FW)
- Notes: Fulham stick with what's working after securing three points, though they start Reed after he came on for Mario Lemina after the break against West Brom.
Leeds United at Crystal Palace
- Previous Result: 1-4 loss v. Leicester City (Monday)
- Out: Kalvin Phillips (shoulder), Gaetano Berardi (knee), Adam Forshaw (hip), Rodrigo (COVID-19), Diego Llorente (groin)
- Questionable: Raphinha (ankle)
- Projected Lineup (4-1-4-1 v. Crystal Palace): Illan Meslier (GK), Liam Cooper (DC) Luke Ayling (DL), Robin Koch (DC), Stuart Dallas (DR), Jamie Shackleton (MC), Mateusz Klich (DMC), Helder Costa (MR), Jack Harrison (ML), Pablo Hernandez (MC), Patrick Bamford (FW)
- Notes: Leeds run things back with their starting XI and chalk up the Leicester loss as unlucky.
Leicester City v. Wolverhampton
- Previous Result: 1-4 win at Leeds United (Monday)
- Out: Caglar Soyuncu (groin), Wilfred Ndidi (groin), Ricardo Pereira (knee), Timothy Castagne (hamstring)
- Questionable: Jonny Evans (back), Daniel Amartey (hamstring)
- Previous Europa League Lineup (Thurs., Nov. 5): Kasper Schmeichel (GK), Marc Albrighton (MR), Christian Fuchs (DC), Wesley Fofana (DC), James Justin (DC), Luke Thomas (ML), Hamza Choudhury (MC), Youri Tielemans (MC), James Maddison (AMC), Cengiz Under (AMC), Kelechi Iheanacho (FW)
- Projected Lineup (3-4-2-1 v. Wolverhampton): Kasper Schmeichel (GK), Marc Albrighton (MR), Jonny Evans (DC), Wesley Fofana (DC), James Justin (DC), Luke Thomas (ML), Nampalys Mendy (MC), Youri Tielemans (MC), Harvey Barnes (AMC), Dennis Praet (AMC), Jamie Vardy (FW)
- Notes: If Leicester continue in a 3-4-2-1, they'll have decisions to make if James Maddison moves back into the starting XI. However, after going the full 90 Thursday, he's on the bench, keeping Praet in the XI. Evans should replace Fuchs on the back line if healthy.
Liverpool at Manchester City
- Previous Result: 2-1 win v. West Ham (Saturday), 0-5 win at Atalanta (Tuesday)
- Out: Virgil van Dijk (knee), Fabinho (hamstring), Alex Oxlade-Chamberlain (knee), Thiago Alcantara (knee)
- Questionable:
- Previous Champions League Lineup (Tues., Nov. 3): Alisson Becker (GK), Andrew Robertson (DL), Rhys Williams (DC), Joe Gomez (DC), Trent Alexander-Arnold (DR), Jordan Henderson (MC), Georginio Wijnaldum (MC), Curtis Jones (MC) Sadio Mane (AML), Diogo Jota (FW), Mohamed Salah (FW)
- Projected Lineup (4-3-3 v. Manchester City): Alisson Becker (GK), Andrew Robertson (DL), Joel Matip (DC), Joe Gomez (DC), Trent Alexander-Arnold (DR), Jordan Henderson (MC), Georginio Wijnaldum (MC), Curtis Jones (MC) Sadio Mane (FWL), Diogo Jota (FWR), Mohamed Salah (FW)
- Notes: It's hard to keep Jota out of the XI, so he remains a starter with Firmino moving to the bench. Liverpool stick with their trusted 4-3-3 formation instead of the 4-2-3-1 employed against Sheffield United a couple weeks ago.
Manchester City v. Liverpool
- Previous Results: 0-1 win at Sheffield United (Saturday), 3-0 win v. Olympiacos (Tuesday)
- Out: Sergio Aguero (hamstring), Fernandinho (leg), Benjamin Mendy (undisclosed), Scott Carson (undisclosed)
- Questionable:
- Previous Champions League Lineup (Tues., Nov. 3): Ederson (GK), Oleksandr Zinchenko (DL), Nathan Ake (DC), John Stones (DC), Kyle Walker (DR), Phil Foden (MC), Ilkay Gundogan (MC), Kevin De Bruyne (MC), Riyad Mahrez (AMR), Raheem Sterling (AML), Ferran Torres (FW)
- Projected Lineup (4-3-3 v. Liverpool): Ederson (GK), Joao Cancelo (DL), Ruben Dias (DC), Aymeric Laporte (DC), Kyle Walker (DR), Bernardo Silva (MC), Rodri (MC), Kevin De Bruyne (MC), Riyad Mahrez (FWR), Raheem Sterling (FWL), Gabriel Jesus (FW)
- Notes: Jesus is back in the XI, which pushes Phil Foden to the bench. Pep Guardiola uses his preferred XI with the international break ahead.
Manchester United at Everton
- Previous Results: 0-1 loss v. Arsenal (Sunday), 2-1 loss at Istanbul Basaksehir (Wednesday)
- Out: Jesse Lingard (undisclosed), Phil Jones (knee), Eric Bailly (undisclosed)
- Questionable: Alex Telles (COVID-19), Victor Lindelof (back)
- Previous Champions League Lineup (Wed., Nov. 4): David de Gea (GK), Aaron Wan-Bissaka (DR), Axel Tuanzebe (DC), Harry Maguire (DC), Luke Shaw (DL), Donny van de Beek (DMC), Nemanja Matic (DMC), Juan Mata (AMR), Bruno Fernandes (AMC), Anthony Martial (FW), Marcus Rashford (AML)
- Projected Lineup (4-2-3-1 v. Everton): David de Gea (GK), Aaron Wan-Bissaka (DR), Axel Tuanzebe (DC), Harry Maguire (DC), Luke Shaw (DL), Scott McTominay (DMC), Fred (DMC), Mason Greenwood (AMR), Bruno Fernandes (AMC), Anthony Martial (FW), Marcus Rashford (AML)
- Notes: Man United return to their trusted 4-2-3-1 with Martial back from suspension, though they use McTominay and Fred together in the midfield again after having recent success together. Tuanzebe stays in the starting XI after taking the spot of Lindelof midweek.
Newcastle United at Southampton
- Previous Result: 2-1 win v. Everton (Sunday)
- Out: Jonjo Shelvey (groin), Matt Ritchie (shoulder), Dwight Gayle (knee), Martin Dubravka (heel), DeAndre Yedlin (undisclosed), Paul Dummett (undisclosed)
- Questionable: Allan Saint-Maximin (bruise)
- Projected Lineup (5-3-2 v. Southampton): Karl Darlow (GK), Fabian Schar (DC), Federico Fernandez (DC), Jamaal Lascelles (DC), Jamal Lewis (DL), Jacob Murphy (DR), Jeff Hendrick (MC), Sean Longstaff (MC), Miguel Almiron (MC), Allan Saint-Maximin (FW), Callum Wilson (FW)
- Notes: Newcastle keep the same squad following their win over Everton.
Sheffield United at Chelsea
- Previous Result: 0-1 loss v. Manchester City (Saturday)
- Out: John Fleck (back), Lys Mousset (toe), Jack O'Connell (knee), Ethan Ampadu (contract)
- Questionable:
- Projected Lineup (3-5-2 v. Chelsea): Aaron Ramsdale (GK), John Egan (DC), Enda Stevens (DC), Chris Basham (DC), George Baldock (MR), Sander Berge (MC), Max Lowe (ML), Oliver Norwood (MC), Ben Osborn (MC), Rhian Brewster (FW), Oliver McBurnie (FW)
- Notes: Lowe has impressed in limited time and keeps his spot in the starting XI, while Norwood re-enters for Ampadu..
Southampton v. Newcastle United
- Previous Result: 3-4 win at Aston Villa (Sunday)
- Out: Ryan Bertrand (hamstring), Danny Ings (knee), Mohammed Salisu (undisclosed), Jake Vokins (undisclosed)
- Questionable: William Smallbone (thigh), Ibrahima Diallo (leg), Jan Bednarek (concussion)
- Projected Lineup (4-4-2 v. Newastle): Alex McCarthy (GK), Kyle Walker-Peters (DR), Jack Stephens (DC), Jannik Vestergaard (DC), James Ward-Prowse (DL), Theo Walcott (ML), Oriol Romeu (MC), Nathan Redmond (MC), Stuart Armstrong (MR), Che Adams (FW), Shane Long (FW)
- Notes: Stephens and Long come into the XI for Bednarek and Ings, respectively. There's a chance Redmond enters the midfield, pushing Ward-Prowse to left-back where the Saints have no other options.
Tottenham Hotspur at West Bromwich Albion
- Previous Results: 2-1 win v. Brighton (Sunday)
- Out: Erik Lamela (undisclosed)
- Questionable: Sergio Reguilon (illness), Serge Aurier (undisclosed), Japhet Tanganga (thigh)
- Previous Europa League Lineup (Thurs., Nov. 5): Joe Hart (GK), Matt Doherty (DR), Toby Alderweireld (DC), Eric Dier (DC), Ben Davies (DL), Harry Winks (DMC), Moussa Sissoko (DMC), Giovani Lo Celso (AMC), Lucas Moura (AMR), Gareth Bale (AML), Harry Kane (FW)
- Projected Lineup (4-2-3-1 v. West Brom): Hugo Lloris (GK), Matt Doherty (DR), Toby Alderweireld (DC), Eric Dier (DC), Sergio Reguilon (DL), Pierre-Emile Hojbjerg (DMC), Moussa Sissoko (DMC), Tanguy Ndombele (AMC), Lucas Moura (AMR), Son Heung-Min (AML), Harry Kane (FW)
- Notes: Reguilon could miss out with the flu, which would give Ben Davies another start at left-back.
West Bromwich Albion v. Tottenham Hotspur
- Previous Result: 0-2 loss at Fulham (Monday)
- Out: Hal Robson-Kanu (arm), Sam Field (knee)
- Questionable: Dara O'Shea (ankle)
- Projected Lineup (4-1-4-1 v. Tottenham): Sam Johnstone (GK), Darnell Furlong (DR), Semi Ajayi (DC), Branislav Ivanovic (DC), Conor Townsend (DL), Jake Livermore (DMC), Conor Gallagher (MC), Filip Krovinovic (MC), Matheus Pereira (MR), Grady Diangana (ML), Karlan Grant (FW)
- Notes: There's a chance Slaven Bilic changes things up given recent results, but he doesn't have a ton of options unless guys like Kieran Gibbs or Matthew Phillips enter the call.
West Ham United v. Fulham
- Previous Result: 1-2 loss at Liverpool (Saturday)
- Out: Michail Antonio (hamstring)
- Questionable:
- Projected Lineup (5-4-1 v. Fulham): Lukasz Fabianski (GK), Vladimir Coufal (DR), Aaron Cresswell (DC), Angelo Ogbonna (DC), Fabian Balbuena (DC), Arthur Masuaku (DL), Jarrod Bowen (MR), Declan Rice (MC), Tomas Soucek (MC), Pablo Fornals (ML), Sebastien Haller (FW)
- Notes: Everything stays the same for the Hammers with Haller still up front in place of Antonio.
Wolverhampton at Leicester City
- Previous Result: 2-0 win v. Crystal Palace (Friday)
- Out: Jonny (knee)
- Questionable: Fernando Marcal (undisclosed)
- Projected Lineup (3-4-2-1 v. Leicester City): Rui Patricio (GK), Willy Boly (DC), Conor Coady (DC), Max Kilman (DC), Nelson Semedo (MR), Ruben Neves (MC), Leander Dendoncker (MC), Pedro Neto (MC), Rayan Ait-Nouri (ML), Daniel Podence (FW), Raul Jimenez (FW)
- Notes: Wolves found something with Ait-Nouri out wide and they repeat last week's formation, which led to their best performance of the season.
The author(s) of this article may play in daily fantasy contests including – but not limited to – games that they have provided recommendations or advice on in this article. In the course of playing in these games using their personal accounts, it's possible that they will use players in their lineups or other strategies that differ from the recommendations they have provided above. The recommendations in this article do not necessarily reflect the views of RotoWire. Andrew M. Laird plays in daily fantasy contests using the following accounts: FanDuel: kingmorland, DraftKings: andrewmlaird, Yahoo: Lairdinho. Adam Zdroik plays in daily fantasy contests using the following accounts: FanDuel: zdroik, DraftKings: rotozdroik, Yahoo: StreakMaster.