This article is part of our FanDuel Fantasy Football series.
QUARTERBACK
Deshaun Watson, HOU at TEN ($7,400): Watson didn't play well in New England, finishing with less than 200 passing yards despite throwing 34 passes. The good news is his knee came out of the contest in good shape, and he was able to scramble for 40 yards. The Texans called his number on a running play at the goal line, and his scrambling ability separates himself from at least half the quarterbacks in the league. The Titans don't appear to be a defense to worry about, and most owners will flock to use Ben Roethlisberger or Patrick Mahomes this week with that game expected to be a high-scoring affair.
RUNNING BACK
Tevin Coleman, ATL vs. CAR ($5,900): Using Coleman this week is only an option if Devonta Freeman (knee) is ruled out for sure. When Freeman missed two games last season, Coleman had 19 and 20 carries and scored three touchdowns as well as the primary running back. Carolina's run defense is decent, but they gave up four yards per carry last season, good for only 11th best in the league. James Conner ($7,000) will be the chalky game in cash choice and is still a bargain at his price.
Derrick Henry, TEN vs. HOU ($6,200): Now that cash game options have been discussed, let's move on to a contrarian GPP play. Henry has a disappointing 3.6 fantasy points in Week 1, letting down owners who expected a breakout this season. This week, despite going home, the matchup is worse, as the Texans boast one of the better defenses in the league now that their key players are healthy. However, Henry is still capable of taking it to the end zone on any play, as evidenced by the 61-yard TD run called back due to a phantom holding call against Miami.
WIDE RECEIVER
Chris Hogan, NE at JAC ($6,200): Hogan makes his second straight appearance here despite a lousy showing in Week 1. He's the perfect GPP play this week coming off a poor performance (1.6 fantasy points), and it appears to be a tough matchup going into Jacksonville. A combination of those factors will likely put Hogan below five percent owned despite being the No.1 wide receiver of Tom Brady's. There's a good chance Jalen Ramsey shadows Rob Gronkowski, and it's notable that in last season's Conference Championship Danny Amendola and Brandin Cooks combined for a 13-184-2 line against this same Jacksonville team.
Nelson Agholor, PHI at TB ($6,100): Alshon Jeffery will miss another game, making Agholor the top target among the Eagles wide receivers. While his eight catches for 33 yards isn't spectacular, the 10 targets he got bodes well for this week. The Buccaneers were just torched by Michael Thomas in a shootout, suggesting Tampa Bay may have trouble containing receivers. Nick Foles should be better this week.
TIGHT END
George Kittle, SF vs. DET ($5,600): Rob Gronkowski ($8,100) has a bad matchup, and with Delanie Walker and Greg Olsen out, the position is looking pretty thin. Kittle went 9-5-90 Week 1, which wasn't too bad considering he was on the road against a good defense. It should be easier sledding this week against a Detroit team that was just torched by Quincy Enunwa who plays similarly to a tight end. A stack of Jimmy G, Kittle and some combination of Pierre Garcon or Dante Pettis makes a lot of sense.
FLEX
Jordan Reed, WAS vs. IND ($6,200): It's always an interesting strategy to use a tight end in the FLEX spot as they're often an afterthought to the running backs and wide receivers. The facts on Reed are: 1. He's healthy (for now), 2. Alex Smith is used to throwing to his tight end and 3. It's a great home matchup against a bad defense in the Colts. Reed had a respectable 12.8 fantasy points last week and has the upside to do better than that in this game.
DEFENSE
New York Jets vs. MIA ($3,700): This is $1,100 cheaper than the highest-priced Rams defense and there's a chance the Jets may be a very good defensive team. They conceded only 10 points to the Lions on the road and showed they have the ability to get to the quarterback and create turnovers.