Nate Hamilton picks the FanDuel Week 1 DFS contest. Matt Ryan could be in for a big day in his Colts debut.
Thursday Night Football Picks: NFL Best Bets and Player Props for Los Angeles Rams vs. Buffalo Bills
Mike Barner gets you set for kickoff of the 2022 NFL season with his best bets and player props to target in Thursday's Rams-Bills matchup. Visit RotoWire for more NFL picks and betting analysis all season.
Elijah Mitchell is off the injury report and back on the RB2 map, opening his season against the rebuilding Bears.
Ryan Pohle breaks down the ins and outs of DraftKings' Reignmakers contest.
Sasha Yodashkin looks over the Week 1 Sunday slate and expects Trey Lance to begin his tenure as the 49ers starting QB with a bang against the Bears.
Dan Marcus goes deep into the free-agent pool to find upside adds who could pay off down the road, if not this week.
Erik Siegrist analyzes the Monday night game as Russell Wilson returns to Seattle to take on the Seahawks.
Mike Barner picks the NFL contests for the Thursday night game on Monkey Knife Fight. Can Matthew Stafford outgun Josh Allen?
The Staff agrees that the Vikings as a home dog against the Packers is too good to pass up. Check out the rest of their picks for Week 1.
Nick Whalen offers up his picks for a unique Week 1, including the Ravens and Eagles rolling as road favorites.
Jason Thornbury likes Jonathan Taylor and the Colts on the road against the Texans in Week 1 Survivor.
Even on the road, Josh Allen and the Bills are 2.5-point favorites over the Super Bowl champion Rams to kick off the season.
Jeff Erickson attempts to help you resolve your start/sit dilemmas with his Week 1 Rankings.
Get the latest fantasy football rankings with RotoWire's top 150 players in PPR formats. Find out which players are sliding up and down draft boards.
The Titans are Jerry Donabedian's top streamer for Week 1, but he also likes Myles Garrett and the Browns as a multi-week option thanks to a favorable early schedule.
Jeff Stotts advises that although both are healthy now, Cam Akers and Matthew Stafford have the types of injuries that can linger throughout the season.
Kevin Payne analyzes the top waiver-wire options for Week 1, including Mitch Trubisky, who was named the starter in Pittsburgh.
Michael Rathburn gives an early read on some notable line movements heading into NFL Week 1. Visit RotoWire for more NFL betting picks and analysis all season long.