Injury hotspots for Week 7 include Washington's pass catchers, the Chargers' offensive line, Detroit's secondary and Green Bay's defensive line.
Below you'll find four different categories, with our lists including key offensive linemen and defensive players whose absences might impact fantasy decisions. The bottom section, for potential game-day decisions, is sorted by kickoff times. It can be used as a checklist/cheatsheet for Sunday morning and afternoon when inactives come out and we need to adjust lineups. Before we get to the 'questionable' players, let's see who's definitely in and who's definitely out...
Good to Go 💯
RB Chuba Hubbard (calf)
RB Alvin Kamara (ankle)
RB Bam Knight (knee)
RB Blake Corum (ankle)
WRs CeeDee Lamb (ankle) & KaVontae Turpin (foot)
WRs Marvin Harrison (concussion) & Michael Wilson (foot)
WR Quentin Johnston (hamstring)
WR Chris Olave (hip)
WR DJ Moore (groin)
WR Jauan Jennings (ankle/shoulder)
WR Dyami Brown (shoulder)
WR Jerry Jeudy (knee)
WR Jalin Hyatt (ankle)
WR Van Jefferson (ankle)
WR Tutu Atwell (hamstring)
WR Josh Reynolds (hip)
TE Darren Waller (hip)
TE Ja'Tavion Sanders (ankle)
Dave Canales said the Panthers have internally made a decision on who'll start at running back vs. the Jets and get the majority of carries, but isn't divulging that information.
— Steve Reed (@SteveReedAP) October 17, 2025
Ruled Out/Doubtful 🚑
Out/Doubtful/IR
QB Brock Purdy (toe)
RB Bucky Irving (D - foot)
RB Emari Demercado (ankle)
WR Puka Nacua (ankle)
WRs Ricky Pearsall (knee) & Marquez Valdes-Scantling (IR - calf)
WR Calvin Ridley (hamstring)
WR Terry McLaurin (quad)
WR Garrett Wilson (D - knee)
WRs Josh Downs (concussion) & Ashton Dulin (chest)
WR Darius Slayton (D - hamstring)
WR Chris Godwin (D - fibula)
WR Christian Watson (IR - knee)
WR Ray-Ray McCloud (non-injury)
TE Brock Bowers (knee)
TE David Njoku (knee)
TE Grant Calcaterra (oblique)
K Cairo Santos (thigh)
Potential Workload Beneficiaries (From Injuries Above)
QB Mac Jones
RB Rachaad White
RB Michael Carter
WRs Davante Adams, Jordan Whittington, Tutu Atwell & TE Tyler Higbee
WRs Kendrick Bourne, Jauan Jennings & Demarcus Robinson
WRs Elic Ayomanor & Van Jefferson
WRs Jaylin Lane, Luke McCaffrey & Chris Moore
WRs Josh Reynolds & Arian Smith
WRs Alec Pierce, Adonai Mitchell & Anthony Gould
WRs Lil'Jordan Humphrey & Jalin Hyatt
WRs Tez Johnson & Sterling Shepard
TE Michael Mayer
TEs Harold Fannin & Blake Whiteheart
Key Defensive Players + Offensive Linemen
CB Charvarius Ward (concussion)
CB Trevon Diggs (concussion)
LB Devin Lloyd (calf)
LB Jonah Elliss (shoulder)
OLB Andrew Van Ginkel (neck)
LB Fred Warner (OFS - ankle)
DL Lukas Van Ness (foot) & Devonte Wyatt (knee)
S Brian Branch (suspension) + CB Avonte Maddox (hamstring)
LT Joe Alt (D - ankle) + RT Trey Pipkins (knee) + S Elijah Molden (D - thumb)
C John Michael Schmitz (concussion)
LT Josh Simmons (personal)
Listed as Questionable - Should Play 👍
RB Josh Jacobs (illness)
RB D'Andre Swift (groin)
RB Hassan Haskins (chest)
WR Stefon Diggs (chest)
WR Jalen Coker (IR - quad)
TE George Kittle (IR - hamstring)
Swift is the only guy listed above that wasn't a full practice participant Friday (and he told reporters that he's fine and ready to play).
D'Andre Swift says he will play vs. New Orleans. The groin injury is one that came from the Commanders game but isn't one he thinks will affect him in game. He was limited on Thursday and Friday, more of a product of maintenance than anything else.
— Courtney Cronin (@CourtneyRCronin) October 17, 2025
Shanahan on whether Kittle would need to be eased in like #49ers S Malik Mustapha was last week: "Malik had no training camp, hadn't practiced in a year with his ACL. ... (George has) been preparing the last two weeks to play football, so a little different story." https://t.co/adl9bLyzud
— Noah Furtado (@_noahfurtado) October 17, 2025
Truly Questionable / Game-Time Decisions 🤔
Early Games
WR Jakobi Meyers (knee/toe)
Meyers returned to practice Friday as a limited participant, after sitting out Wednesday and Thursday. With a bye week coming up and trade rumors potentially not far behind, the Raiders would be smart to hold him out if there's any doubt at all. Tre Tucker, Jack Bech and Dont'e Thornton (recently benched for Bech) are the likely beneficiaries if Meyers joins Brock Bowers (knee) on the inactive list.
Late-Afternoon Games
QB Kyler Murray (toe)
WR Deebo Samuel (calf) + TE Zach Ertz (shoulder/calf)
WR Zay Jones (knee)
WR Dontayvion Wicks (leg)
K Brandon McManus (leg)
Samuel returned to practice Friday but didn't sound particularly optimistic when talking with reporters. Ertz seems in less danger of missing Sunday's game, but he did go from DNP to FP to LP and ended up with a 'questionable' tag.
Murray remained limited all week and could come down to a true game-day decision, although it sounds like Jacoby Brissett dominated first-team reps at practice this week.
Deebo Samuel:
On how he's feeling:
"I'm aight."On what it's been like playing with the heel injury:
"It's aggravating for sure."On if there's any doubt about his availability for Sunday:
— Nicki Jhabvala (@NickiJhabvala) October 17, 2025
"We'll just have to see."
Primetime Games
WR Darnell Mooney (hamstring) - SNF
WRs Mike Evans (hamstring) & Emeka Egbuka (hamstring) - MNF
Evans is the only one of Tampa Bay's injured stars with a decent shot to play this week. The team hasn't ruled out Egbuka, so I'm listing him here, but there hasn't been any hint of optimism or practice participation. Evans was a limited participant Thursday, before sitting out Friday.(possibly pre-planned for maintenance).
Key Defensive Players + O-Linemen
LG Damien Lewis (chest)
LT Jake Matthews (ankle)
DT Grady Jarrett (knee)
DT Mason Graham (knee)
CB Kenny Moore (Achilles)
OLB Khalil Mack (IR - elbow) + ILB Denzel Perryman (IR - ankle) + OL Jamaree Salyer (knee)
CB Nate Hobbs (knee) + RT Zach Tom (oblique)
RT Brian O'Neill (knee)
DT Jalen Carter (heel)
LB Lavonte David (knee)
CB Terrion Arnold (shoulder) + S Kerby Joseph (knee) + DJ DJ Reader (back) + LT Taylor Decker (shoulder)
Still looks like a question as to whether the Seahawks' secondary will finally be at full strength Monday vs. Houston.
Devon Witherspoon progressed to a full participant today, but Julian Love remained limited and Riq Woolen went from full to limited.
Derick Hall remained out. pic.twitter.com/ZmgCM8g4Qi
— Brady Henderson (@BradyHenderson) October 17, 2025