With Diego Costa suspended for yellow card accumulation, Chelsea will be looking for Eden Hazard to step up in the attack against an overmatched Bournemouth.
Sergio Aguero is still serving a four-match ban, which means Manchester City may need Kelechi Iheanacho to lead the line against a solid Arsenal defense.
A road game against Manchester City is never an easy one, but if there is anyone up to the task, it's Arsenal's Alexis Sanchez.
With Tottenham expected to easily beat Burnley on Sunday, Harry Kane is likely to be a popular fantasy option.
Adama Traore has looked dangerous in his last few starts, which have come against tough opponents, and Alex Spalding is optimistic the former Barca product can break through Saturday against Swansea.
In his debut column for RotoWire, Kevin Swanson likes Zlatan Ibrahimovic, who has five goals in his last five games, on Saturday against a West Brom defense he should be able to exploit.
The reigning champions are starting to pick it up, but they have a fairly tough matchup at Stoke City on Saturday. Can Jamie Vardy continue his solid play?
With three goals and two assists in his last four games, Diego Costa is likely to get plenty of attention from fantasy players for Wednesday's match against lowly Sunderland.
Manchester City aren't the only heavy favorites on Wednesday's eight-game slate, but RotoWire's Schuyler Redpath explains why Kevin De Bruyne should be a popular fantasy option.
Chelsea's Diego Costa has four goals and three assists in his last six games, and he'll have a great opportunity to add to his totals Wednesday against Sunderland.
Tottenham are the biggest favorites on Wednesday's slate as they welcome Hull City to White Hart Lane, which means Harry Kane will likely get plenty of fantasy attention.
Arsenal have been flying high of late, and plenty of fantasy managers will be targeting their players on Tuesday's two-game slate.
With Sergio Aguero suspended, Kevin De Bruyne is going to have to step up for the Citizens in their road match at Leicester City on Saturday.
Andrew Laird and Mike Gottlieb preview Gameweek 15 of the Premier League, including how much Arsenal will dominate Stoke City and whether Diego Costa is the best fantasy forward in England.
Petr Cech hasn't lost in the Premier League since the opening match of the weekend, and he makes for a solid play Saturday against an overmatched Stoke side.
Mesut Ozil has been fairly goal and assist dependent on FanDuel this season, but RotoWire's Andrew Laird explains why that shouldn't be a problem Saturday against Stoke City.
Arsenal are big favorites Saturday at home against Stoke City, which means Mesut Ozil will likely garner plenty of fantasy attention.
Real Madrid are still fighting for the top spot in their group, and Cristiano Ronaldo will now face off against a leaky Borussia Dortmund defense in Spain.