Chelsea will get very close to clinching the Premier League title with three points Monday against Middlesbrough, and they're likely to rely heavily on Eden Hazard to get there.
Sacha Kljestan's price isn't nearly as high as it's been in the past, and JD Bazzo thinks the Red Bulls midfielder will be a great value Saturday against the Union.
Edin Dzeko has six goals and two assists in his last seven Serie A matches, and he'll look to add to his totals Sunday against AC Milan at the San Siro.
With Manchester United prioritizing the Europa League over their domestic matches, Paul Pogba may not get an opportunity to shine against Arsenal.
Gylfi Sigurdsson ended a 10-match goalless drought last weekend against Manchester United, and he'll now try to find the back of the net against Everton at the Liberty Stadium.
Jamie Vardy has scored seven goals in his last nine games, and no one on Saturday's slate has better anytime goal-scoring odds.
Spurs need to keep winning in order to stay within striking distance of Chelsea for the Premier League title, and they'll look for Harry Kane to make an impact Friday against West Ham.
No one has taken more shots, created more chances or sent in more crosses than Gylfi Sigurdsson among the players on Saturday's five-game slate.
With not many goals expected to be scored during this week's matches, solid peripheral players like Casemiro could be very helpful to fantasy managers.
While the matchup against Atletico Madrid is far from easy, fading Cristiano Ronaldo could be detrimental during this week's two-game Champions League slate.
Kylian Mbappe has been almost unstoppable of late, but he'll now have to face off against arguably the best defensive team in the world.
Nicolas Lodeiro is one of the most expensive players on Saturday's slate, but JD Bazzo explains why the Sounders midfielder is worth the investment.
Manchester City are the biggest favorites on Sunday's three-game slate, which means plenty of fantasy managers are likely to turn to Kevin De Bruyne.
Manuel Lanzini has created a bunch of chances recently, and he'll look to continue doing so against Stoke City at the bet365 Stadium.
With most upper-tier fantasy options missing from Saturday's five-game slate, is it worth paying up for Leicester City's Riyad Mahrez?
Saturday's five-game slate doesn't include many of the Premier League's stars, which means fantasy managers could be drawn to players like Leicester City's Jamie Vardy.
Gonzalo Higuain could be a popular pick on Friday's three-game slate, but he doesn't have the best anytime goal-scoring odds.