Arsenal are expected to rotate heavily ahead of Thursday's Europa League semi-final second leg against Atletico Madrid in Spain, which means fantasy players could target Manchester United attackers.
Atlanta United has scored multiple goals in every home match this season, and they'll look to continue their streak Saturday against Montreal.
Potential rotation in the Liverpool attack could alter some fantasy lineups, but Mohamed Salah will be a popular option if he starts at home to Stoke City.
Liverpool look set to rest regular starters like Mohamed Salah and Roberto Firmino, which should open up a few key value plays when they host Stoke City at Anfield.
An away match to Crystal Palace is not enough for Adam Zdroik to think Riyad Mahrez won't perform for fantasy players Saturday.
Andros Townsend has moved up to the front of Crystal Palace's attack alongside Wilfried Zaha, and Evan Morter loves their upside Saturday against Leicester City.
Potential rotation in the Chelsea lineup could throw a wrench in the plans of fantasy players, but Willian looks like a strong play away to Swansea if he can get the start.
Sevilla are favored away to Levante on Friday, which means fantasy players will likely have Pablo Sarabia in their sights.
Chelsea are the biggest favorites on Saturday's six-game slate, but can fantasy players rely on Eden Hazard with the Blues having nothing left to play for?
Atletico Madrid will try to get an away goal in the opening leg against Arsenal at the Emirates, with Antoine Griezmann shouldering plenty of the attacking load.
Bayern Munich will need a big performance from Robert Lewandowski if they want to get by Real Madrid in the Champions League.
Bayern Munich are favored at home against Real Madrid on Wednesday, and RotoWire's Schuyler Redpath likes the fantasy outlook for former Madrid midfielder James Rodriguez.
The matchup against Bayern Munich in Germany isn't ideal, but RotoWire's Andrew Laird explains why Cristiano Ronaldo should still get plenty of attention from fantasy players.
Liverpool are strong favorites at home against Roma on Tuesday, which means fantasy owners are likely to be targeting Mohamed Salah.
Andrew Laird and Jordan Cooper review their daily fantasy soccer lineups from this past weekend and then preview this week's Champions League semi-final first legs.
Wayne Rooney hasn't scored a Premier League goal since Dec. 18, but he'll try to break his goal-less streak Monday against Newcastle at Goodison Park.
The Etihad will be rocking Sunday when Man City host Swansea City, and there should be plenty of fireworks from the likes of Kevin De Bruyne, Gabriel Jesus and Raheem Sterling.
Manchester City will be celebrating with their supporters Sunday, and plenty is expected from their attackers when they take on Swansea City.