Seahawks vs 49ers Odds, Lines, Spreads & Totals 2025
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Hard Rock 
49ers
23.5 Pts
Seahawks
22.0 Pts
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Moneyline
DraftKings
PROBABILITY with vig removed
49ers Win (-120)
52.2%
Seahawks Win (+100)
47.8%
LINE MOVEMENT
No changes have been recorded yet.
No changes have been recorded yet.
Spread
DraftKings
PROBABILITY with vig removed
Win By 2+ Pts(-108)
49.6%
Win or Lose By < 2 Pts(-112)
50.4%
LINE MOVEMENT
No changes have been recorded yet.
No changes have been recorded yet.
No changes have been recorded yet.
Over Under
DraftKings Points
PROBABILITY with vig removed
Over 46 Total Points(-110)
50.0%
Under 46 Total Points(-110)
50.0%
LINE MOVEMENT
No changes have been recorded yet.
No changes have been recorded yet.
No changes have been recorded yet.
Player Props
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49ers Injury Report
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Seahawks Injury Report
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49ers Lineup
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QB
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RB
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WR
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WR
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WR
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TE
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Inactives
None reported yet.
Seahawks Lineup
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QB
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RB
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WR
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WR
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WR
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TE
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K
Inactives
None reported yet.
49ers News
#1 WR
Brandon Aiyuk: Reportedly thriving in workouts
Jun 13th
San Francisco general manager John Lynch said Thursday that Aiyuk (knee) has been "doing a tremendous job coming back," Kevin Patra of NFL.com reports.
#1 RB
Christian McCaffrey: Participates fully in minicamp
Jun 12th
McCaffrey was one of a few 49ers veterans to participate in 11-on-11 work during mandatory minicamp, Matt Barrows of The Athletic reports.
#2 WR
Jauan Jennings: Bothered by calf
Jun 12th
Jennings dealt with a minor calf injury during the offseason program, Matt Barrows of The Athletic reports.
Seahawks News