With Sergio Aguero sidelined due to injury, many fantasy players are likely to turn to Kevin De Bruyne on Monday's two-game slate.
There are three strong favorites on Sunday's three-game slate, but Marseille have the highest implied goal total, which could push people toward Florian Thauvin.
Josef Martinez is likely to be a popular fantasy option Sunday as Atlanta United host D.C. United in their home opener.
Tottenham suffered a crushing loss to Juventus in the Champions League on Wednesday, but they'll look to bounce back against Bournemouth at the Vitality Stadium.
Tigres and Club America are both home favorites on Saturday's two-game slate, but there could still be plenty of fantasy points to be had among all four teams.
Lionel Messi is unavailable for Saturday's match against Malaga, which means fantasy players won't necessarily have their guaranteed goal.
The Red Bulls may not have the highest win odds on Saturday's four-game late slate, but no one has better anytime goal scoring odds than Bradley Wright-Phillips.
Alvaro Morata's spot in the starting XI isn't guaranteed, but he could be a huge reward for fantasy managers willing to risk it.
Real Salt Lake will host expansion-side LAFC on Saturday, likely pushing plenty of fantasy players toward Albert Rusnak.
With few forwards to pay up for, Chelsea midfielder Eden Hazard could be the highest-owned player on Saturday's six-game slate.
Chelsea are big favorites at home to Crystal Palace on Saturday, and with few elite goal scorers to pay up for, many fantasy players will be stacking the Chelsea defense.
Morelia are the big favorites on Friday's two-game slate, as the bookmakers expect them to easily handle 14th-place Veracruz.
Andrew Laird and Mike Gottlieb preview Gameweek 30 of the Premier League, including whether Burnley will start to fall off now that they've reached 40 points and whether Manchester City can answer the biggest question of all: can they do it on a cold nigh
Chelsea's attackers have been a bit inconsistent this season, but Willian may be too hard to pass up at home against Crystal Palace.
Andrew Laird, JD Bazzo and Schuyler Redpath discuss their reactions to the new rules in MLS Fantasy after the opening weekend, including how their switcheroos worked out, and then they preview the nine-game Round 2 slate.
Radamel Falcao has been sidelined for the past month with a thigh injury, but he is expected to return Friday to face Strasbourg and comes in with the best anytime goal scorer odds on DraftKings' three-game slate.
Atlanta United took a pounding last weekend against the Dynamo, but they have a great opportunity to bounce back in their home opener against D.C. United, which should push people toward Miguel Almiron for their fantasy captain.
Andrew Laird and Jordan Cooper review this week's Champions League action before previewing Saturday's six-game daily fantasy Premier League slate, which only includes one top-six team and a ton of recognizable set-piece takers.