Portland are favored at home against Toronto on Wednesday, which could push fantasy players to rostering Diego Valeri.
PSV Eindhoven are the biggest favorites on Wednesday's three-game slate, but fantasy players will have to decide how much they want to pay up for their stars.
With two games in Week 27, many fantasy managers will be tempted to give the captain's armband to Wayne Rooney, but RotoWire's Adam Zdroik wonders if another D.C. United attacker is more deserving.
Sergio Aguero has only scored in one of three starts this season, but he has a great opportunity to find the back of the net Saturday at home against Newcastle.
There are eight teams playing twice in Week 27, which helps push Toronto FC's Sebastian Giovinco to the top of one of JD Bazzo's positional rankings.
Ajax have a commanding 3-1 aggregate lead over Dynamo Kyiv after the first leg in the Netherlands, and they are favored to win in Ukraine on Tuesday.
Andrew Laird and Jordan Cooper review Saturday's five-game daily fantasy Premier League slate, including whether fading Mohamed Salah in cash games was a justified risk or a mistake.
Paul Pogba has scored from the penalty spot in each of the first two matches this season, and he could be a popular GPP option Monday against Spurs.
The Red Bulls will take on a resurgent D.C. United on Sunday, and they'll likely rely on Bradley Wright-Phillips to lead the charge.
First-place Cruz Azul visits third-place Santos Laguna on Sunday, but fantasy players may be better off focusing on Toluca at home against Leon.
Toronto is the second-biggest favorite on Saturday's five-game MLS slate, which means fantasy players will surely be targeting Sebastian Giovinco.
Eden Hazard is apparently not ready to play a full 90 minutes yet, but fantasy players could be tempted to roster him anyway if he starts Sunday at Newcastle.
Josef Martinez has already tied the MLS single-season goal-scoring record, and he'll look to take control of it in Orlando on Friday.
A home match against Brighton is likely to see plenty of people trying to stack Liverpool this weekend, according to RotoWire's Schuyler Redpath.
Lyon are big favorites at home to Strasbroug on Friday, and Memphis Depay could be a very popular fantasy option.
There are likely to be plenty of Liverpool stacks on Saturday's six-game slate, but RotoWire's Chris Owen explains why fantasy players shouldn't forget about Manchester City.
Mohamed Salah figures to be a very popular play on Saturday's five-game slate, and while fantasy players could pivot to Sadio Mane, RotoWire's Andrew Laird explains why Roberto Firmino may be the better alternative.
Mohamed Salah and Sadio Mane are attractive plays for Saturday's five-game slate, and RotoWire's Adam Zdroik dives in to explain why one makes more sense than the other.