Champions League Best Bets: Picks, Odds & Predictions for Tuesday, Nov. 25

Champions League best bets for Tuesday, Nov. 25 include Ajax vs Benfica, Newcastle United vs Marseille, FC Barcelona vs Chelsea and Bayer Leverkusen vs Manchester City.
Champions League Best Bets: Picks, Odds & Predictions for Tuesday, Nov. 25
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Champions League Best Bets: Picks, Odds & Predictions for Tuesday, Nov. 25

Tuesday's UEFA Champions League schedule features nine matches, and we've identified the best bets, top predictions and most valuable odds across the slate. This breakdown highlights four recommended plays—covering match-winner picks, goal-scorer props and a plus-money parlay—centered around key fixtures such as Chelsea vs Barcelona at Stamford Bridge. These are the bets with the strongest statistical and matchup-based edges for Tuesday's Champions League action.

Knowing injuries and predicted lineups (and eventually confirmed) for Champions League matches is always useful before betting matches. Check out our lineups page to get all the info.

UEFA Champions League Best Bet for Benfica at Ajax

Benfica to win -113

This is a massive game for both clubs, as both Benfica and Ajax have yet to record a point in the current league phase. The playoff spots are only four points away, so winning here is crucial if either of these two giants wants to keep their qualification dreams alive for another week. It's hard to trust either side to get the victory here, but we're backing Benfica to pull the upset here -- even if they've struggled badly in the European stage when they've had to play on the road. 

The Eagles won three of their last five away matches in all competitions (W3, D1, L1) and have kept back-to-back clean-sheet wins at home at the domestic level. Playing on the road in the Champions League is a different level of competition, but they'll be facing an Ajax side that owns the worst defensive record in the competition with 14 goals allowed. Ajax lost 3-0 to Galatasaray in their previous home match in the Champions League and are in the midst of  four-game winless streak at the Johan Cruyff Arena across all competitions (D1, L3).

UEFA Champions League SGP for Newcastle United at Marseille

Over 2.5 goals and both teams to score -104

Newcastle United have a tough trip lined up to Marseille, one of the best teams in Ligue 1, but this game couldn't have come at a better time for the Mapgies. Eddie Howe's men are coming off a 2-1 win over Manchester City in the Premier League and are on an excellent run of results with seven wins in their last 10 matches across all competitions, including a three-game winning streak in the Champions League.

Marseille need points, though. Despite strong results at the domestic level, including a three-game winning streak following a 5-1 away win over Nice the last time out, their Champions League campaign has been disappointing with three losses out of four matches, including back-to-back ones against Sporting CP and Atalanta. Marseille have at least found the back of the net in three of those games, and given the way they've been playing lately, this game could see both sides find the back of the net and over 2.5 total goals. Three of Newcastle's four Champions League matches have had at least three goals, and the same has happened in three of Marseille's.

UEFA Champions League Moneyline for Barcelona at Chelsea

FC Barcelona to win +173

The matchup between FC Barcelona and Chelsea is the marquee game of Tuesday's nine-game slate, and since both sides are tied at seven points in the standings, this meeting at Stamford Bridge could have huge qualification implications. Both teams enter this fixture with the same form over their previous four matches in all competitions (W3, D1), but Barcelona have been nearly unstoppable in front of goal, scoring 14 goals over that span, including four past Athletic Club this past weekend. 

Chelsea are coming off back-to-back clean-sheet wins over Wolverhampton and Burnley, but Barça represent a whole new level of opposition compared to those two Premier League rivals. Chelsea have won their two home matches in the current Champions League, but those wins came against two struggling sides in Benfica and Ajax. Barcelona should have enough quality to breeze past the Blues despite playing on the road, mainly based on how good they've been offensively of late and the fact that they're recovering key players at full fitness, such as Raphinha, Lamine Yamal and Joan Garcia, ahead of this fixture.

UEFA Champions League Goalscoring Bet for Bayer Leverkusen at Manchester City

Erling Haaland to score first goal +215

Last but not least, we have to back Erling Haaland against a Bundesliga opponent. Even though the Norwegian striker didn't score in the 2-1 loss to Newcastle this past weekend, it's worth noting that he's been on fire lately with goals in each of his last five Champions League matches, as well as in 17 of his previous 19 matches between club and country across all competitions. 

Haaland also has two goals in his last two head-to-head meetings against a Leverkusen side that's averaging 2.5 goals conceded per match in the current Champions League campaign. Knowing that Haaland has opened the scoring in three of City's four Champions League matches in the current campaign, he's as good a bet as any to do so again while facing a team he knows well from his previous stint at Dortmund.

Champions League Betting Picks Tuesday, November 25

  • Ajax vs. Benfica: Benfica to win -113
  • Chelsea vs. FC Barcelona: FC Barcelona to win +173
  • Marseille vs. Newcastle United: Over 2.5 goals and both teams to score -104
  • Manchester City vs. Bayer Leverkusen: Erling Haaland to score first goal +215

Visit RotoWire all season for exclusive sports betting picks and our weekly Premier League betting show. Remember that betting apps vary in terms of odds, so we have an easy-to-use odds page that allows you to shop for the best lines at DraftKings, FanDuel, BetMGM and PointsBet. Claim over a thousand dollars in bonuses by signing up at the best sports betting sites using the best sportsbook promos.

ABOUT THE AUTHOR
35-year-old sports analyst and journalist. Fan of every single sport on this earth, but mainly NBA, MLB, NFL, NHL and soccer. Eternal optimistic who, for unknown reasons, chose to root for the Chicago Cubs and Jacksonville Jaguars. Born and raised in Chile.
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