Bojan Dubljevic and Valencia head to Turkey to face off against first-place Efes.
Maodo Lo and Bayern head to Spain to take on a surging Barcelona squad and close out Round 28.
Leo Westermann and Fenerbahce take on Khimi in a pivotal matchup for both squads.
Walter Tavares has been all business of late, and he will help lead the Real Madrid charge against ASVEL on Thursday.
There will be plenty of Zs in Sibur Arena on Thursday, but no one will be sleeping when Zenit and Zalgiris get Round 28 underway.
Guards will be the focus in this Round 27 matchup, as Efes' talented backcourt goes up against Scottie Wilbekin and Maccabi.
Defense will be the name of the game when Red Star and Fenerbahce square off in Turkey on Wednesday.
The Mediolanum Forum will be quiet Tuesday without any fans in attendance, but Facundo Campazzo and Real Madrid will take on Milan anyway.
Every team in the EuroLeague plays two games this week, and the action gets underway Tuesday when Austin Hollins and Zenit head south to take on CSKA.
Derrick Williams and Fenerbahce head to Spain to take on Valencia and bring Friday's action to a close.
Friday's action gets underway with David Lighty and ASVEL squaring off against Khimki in Russia.
Red Star heads west to take on Shavon Shields and Baskonia in the final game on Thursday's slate.
Barcelona will attempt to stifle a potent CSKA attack when the two teams square off in Moscow on Thursday.
This week's action gets underway Monday as Panathinaikos heads to Spain to take on Rudy Fernandez and Real Madrid.
Valencia and Maccabi, both missing several key players, bring Round 25 to a close at 3:00 ET.
A pair of teams currently in playoff position will match up when Adam Hanga and Barcelona head to Greece to take on Panathinaikos.
Friday's action gets underway when Billy Baron and Crvena Zvezda host CSKA at 1:00 ET.
Zach LeDay and Zalgiris take on Baskonia in the final game on Thursday's schedule.