Zlatan Ibrahimovic has gone four straight games without a goal, but he'll look to break out of his funk Monday at Montreal.
Sunday's marquee matchup of the Red Bulls at Atlanta United figures to have plenty of fireworks, pushing fantasy players toward Miguel Almiron.
NYC FC is expected to handle the Rapids at Yankee Stadium on Saturday, which means Maxi Moralez could be a popular fantasy option.
Chelsea missed out on qualifying for next season's Champions League, but they still have an opportunity to win a trophy Saturday against Manchester United.
Toronto will be without Sebastian Giovinco and Jozy Altidore on Friday, but they are still strong favorites to beat Orlando City.
Thursday's opening leg of the 2018 Clausura final is expected to be a tightly contested affair, with Santos favored as the home team.
The Whitecaps are heavily favored at home against the Earthquakes on Wednesday, but will fantasy players trust Kei Kamara to find the back of the net?
Atletico Madrid are strong favorites to beat Marseille in the Europa League final on Wednesday, with Antoine Griezmann coming in with the best anytime goal scorer odds.
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Marcus Rashford is likely to have plenty of opportunities Sunday at Watford, and his price makes him well worth consideration.
Harry Kane's quest for his third consecutive Golden Boot will likely have him firing plenty of shots Sunday at home against Leicester City.
Liverpool at home against Brighton sure makes for a great matchup for Mohamed Salah, who is looking to clinch the Premier League single-season scoring record Sunday.
Diego Valeri has four goals in his last five games, and he'll look to stay hot Sunday at home against the Sounders.
Paris Saint-Germain continue to be without Neymar and will miss Edinson Cavani on Saturday, which means Kylian Mbappe will need to step up against Rennes.
Ignacio Piatti failed to do much during the Impact's midweek match at Chicago, but he has a great opportunity to bounce back Saturday at home against the Union.
Chelsea need a win at St. James' Park and help from Brighton to secure Champions League football for next season, which means they'll need a big performance from Eden Hazard.
Another season in the Champions League is in reach for Liverpool, and they'll likely rely on Mohamed Salah to get them there.
Houston travel to Vancouver to take on the Whitecaps on Friday night, and the Dynamo will look for Alberth Elis to make an impact.