Yaya Toure stays in our top-10 this week, but it's a teammate of his that takes the top midfielder spot.
With Robin van Persie and Wayne Rooney back from their respective injuries, there isn't much room left for Danny Welbeck in the Manchester United starting XI.
Romelu Lukaku will be out for a number of weeks with an ankle injury, and Chris Mosinski has a few low-cost options (including one of Lukaku's teammates) to fill the void.
Aaron Ramsey suffered a setback in his recovery from a thigh injury and will miss out yet again.
Robin van Persie returned from injury Tuesday against Cardiff City and scored six minutes into the match. Nick Pitner sees more productive play this weekend from the Dutchman.
A home match against Crystal Palace puts Mesut Ozil at the top of our midfielder rankings this gameweek.
After returning from a calf injury, Sergio Aguero has scored six times in his last four matches in all competitions.
After finishing up a warm-weather training trip in Egypt, Wayne Rooney looks set to return to a Manchester United side that will also include newly-signed Juan Mata.
Romelu Lukaku was brought to Everton to be a big scoring threat, but one of his lower-priced teammates has taken that role on lately.
With goals in back-to-back league matches, Christian Benteke checks in as the No. 3 overall player this gameweek.
Christian Benteke saw his value drop after going nearly four months without a league goal, but he's heating up after scoring in back-to-back matches.
Only Romelu Lukaku has been involved in more Everton goals this season than Kevin Mirallas, who continues to be an undervalued asset.
A home match against Fulham makes Mesut Ozil one of three Arsenal players in this week's Best XI.
Aaron Ramsey looks set to return for Arsenal, after sitting out since Boxing Day with a thigh injury.
After bagging a brace last weekend, Luis Suarez tops the Matchweek 22 rankings.
Can the return of Daniel Sturridge make Luis Suarez even more dangerous?
Luis Suarez continues to be the most expensive option in most salary cap leagues. If you want to shell out the big bucks, you'll need to find low-cost value elsewhere.
Yaya Toure suffered an ankle injury in Wednesday's FA Cup rout of West Ham, and he faces a late fitness test ahead of Sunday's match at Newcastle.