Gonzalo Higuain could be a popular pick on Friday's three-game slate, but he doesn't have the best anytime goal-scoring odds.
Manchester City appear to have the easiest matchup of the weekend fixtures, which means plenty of fantasy managers will consider Sergio Aguero for the captain's armband.
While the Dynamo have been better than expected this season, that's not stopping Adam Zdroik from making Sebastian Giovinco his top captain option this weekend.
Manchester City face off against lowly Middlesbrough this weekend, which pushes Kevin De Bruyne up the positional rankings.
Sporting KC have a solid matchup at home against Real Salt Lake this weekend, and our MLS fantasy experts are high on Jimmy Medranda.
The Manchester derby will get plenty of attention, but it may not be the best place for fantasy points on Thursday's three-game slate.
With a number of upper-tier options to choose from on Wednesday's three-game slate, Middlesbrough's Adama Traore could be a key salary-saving option.
Spurs are favored against Crystal Palace at Selhurst Park on Wednesday, but is Harry Kane the player to focus on for exposure to their dominant attack?
Arsenal are the biggest favorites on Wednesday's three-game slate, which means plenty of fantasy owners will be looking toward Alexis Sanchez.
Diego Costa has gone five consecutive Premier League matches without scoring a goal, but he has the best anytime goal-scoring odds for Tuesday's three-game slate.
Edin Dzeko has been dominant in Serie A action this season, and he'll look to continue his solid play Monday against relegation-bound Pescara.
With Zlatan Ibrahimovic out for the rest of the season with a knee injury, will Henrikh Mkhitaryan be the one who steps up for Manchester United on Sunday against Burnley?
Real Madrid booked their ticket to the semifinal of the Champions League earlier this week, and they'll now take on their hated rival at the Santiago Bernabeu.
Kei Kamara has been a disappointing fantasy option for much of this season, but Adam Zdroik explains why he could break out Saturday against D.C. United.
Andrew Laird and Chris Owen preview the upcoming weekend of Premier League matches, including whether fantasy owners should roll with Romelu Lukaku or Gylfi Sigurdsson in DFS contests, or possibly try to fit them both in.
With Bafetimbi Gomis suspended Friday, who will step up for Marseille as they take on an overmatched Nancy?
Romelu Lukaku's price is very high for Saturday's four-game slate, but Andrew Laird explains why paying up for the Everton striker is worth it.
After a tough run of fixtures for Swansea City, a home match against Stoke City could be just what helps Gylfi Sigurdsson break out with a big game.