David Villa picked up an assist in the season opener at Sporting KC, but he'll look to score the goals himself when NYC FC host the Galaxy on Sunday.
Chelsea are the only top-six club on Saturday's six-game slate, and they're high win odds and implied goal total will help Eden Hazard be a popular fantasy option.
Marseille have a number of solid fantasy options, and they'll all be tested in a home match against Athletic Club on Thursday.
Atletico Madrid are the biggest favorites and have the highest implied goal total on Thursday's early Europa League slate, which means many eyes will be on Antoine Griezmann.
Harry Kane's four-match goal streak ended last weekend against Huddersfield, but he has a great opportunity to start a new one Sunday at Bournemouth.
Manchester City's path to the title will go through Stoke in Gameweek 30, which helps push Kevin De Bruyne to the top of our weekly rankings.
A win Wednesday would book Tottenham's ticket to the quarterfinal, and they'll be relying on Harry Kane to try and get them there.
Fantasy players are likely to be keying on Harry Kane and Gabriel Jesus for their two forward spots, but Evan Morter says those looking for a differential should turn to Paulo Dybala.
Tottenham have the advantage over Juventus after scoring two goals in Turin in the first leg, but that doesn't mean Christian Eriksen will be sitting back in Wednesday's deciding match.
Despite being up 5-0 on aggregate, Liverpool are likely to attack Porto again Tuesday, which means plenty of fantasy players will be keying on Mohamed Salah.
PSG will try to overcome a two-goal deficit without Neymar, which means more of the attacking responsibilities will fall to former Real Madrid attacker Angel Di Maria.
Real Madrid head to Paris with a two-goal aggregate lead, but that isn't likely to stop Cristiano Ronaldo from trying to add to his UCL-leading goal total.
Andrew Laird and Jordan Cooper review this past Saturday's daily fantasy Premier League slate before previewing this week's Champions League action, including whether it's worth saving money with Edinson Cavani instead of paying up for Cristiano Ronaldo.
Liverpool scored five goals in the first leg at Porto, and such a commanding lead could see manager Jurgen Klopp rotate some of his best fantasy producers.
Manchester United are away to Crystal Palace on Monday, a situation that could have fantasy players putting Romelu Lukaku under the microscope.
Locking in value from the early game is a strong strategy on The Six, which puts Wayne Rooney in play for Saturday's seven-game slate.
Riyad Mahrez seems back to his normal self after losing out on a transfer request in January, and he has an excellent matchup Saturday at home against Bournemouth.
Christian Eriksen has scored double-digit fantasy points in seven of his last eight games, and he has a good chance of doing it again Saturday against Huddersfield.