Justin Jefferson will almost certainly have a big game Sunday, and the Colts pass defense is weak enough for Jordan Addison to get rolling in the same game.
The showdown between Detroit and Dallas could set up a punch-for-punch heavyweight contest where CeeDee Lamb and Amon-Ra St. Brown both go off.
Mike Barner has his Week 5 Thursday Night Football Betting Picks for Washington Commanders vs. Chicago Bears.
Jerry Donabedian sifts through Friday injury reports for anything and everything that might be useful for fantasy, including a Niners report that hints at Brandon Aiyuk having a big Week 4.
Drake London is due for a bounce-back after no catches in Week 1, but Jaire Alexander could deny it anyway.