The Texans insist on playing safeties in the slot, which might be a way of asking for trouble from Ladd McConkey.
Justin Jefferson looks truly unstoppable in a game where the Vikings need points and the Lions probably can't cover.
Michael Pittman could be a challenging cover for the Giants' shorter and light cornerbacks.
Michael Penix is unproven, but the quarterback change gives new hope to Falcons pass catchers like Drake London.
Ever since Marshon Lattimore switched teams, Washington's Week 15 matchup with New Orleans became a good matchup for Terry McLaurin.
Now that he's off the injury report, Mike Evans should be set up for a strong game against Las Vegas.
Terry McLaurin should stay hot against a Titans defense starting its third- and fourth-string corners on the boundary.
Juan Carlos Blanco breaks down the latest on the Week 12 injury landscape as of Sunday morning, including news on the 49ers' Brock Purdy.
The 49ers get George Kittle back this week, but it might not matter with QB Brock Purdy and DE Nick Bosa ruled out. Get the full Friday breakdown from RW's Jerry Donabedian.
Audric Estime got off to a strong start this past Sunday and pushed Javonte Williams aside, leading the Denver backfield in snaps and carries by a comfortable margin.
Deebo Samuel could go nuts as the desperate 49ers take aim at a weak Tampa Bay corner rotation.
Justin Jefferson will almost certainly have a big game Sunday, and the Colts pass defense is weak enough for Jordan Addison to get rolling in the same game.
With Tua Tagovailoa back in the lineup Jaylen Waddle should get rolling against Arizona, and the same is true of Tyreek Hill if he plays through his foot injury.
Drake London's breakout should continue against a Seattle secondary that might be without its two starting boundary corners.
The showdown between Detroit and Dallas could set up a punch-for-punch heavyweight contest where CeeDee Lamb and Amon-Ra St. Brown both go off.
George Pickens should get going against an Indianapolis defense with questionable boundary personnel
If Patrick Surtain shadows Mike Evans on the boundary then it could create a target funnel to Chris Godwin in the slot.
Jerry Donabedian breaks down all the injury news from Friday, including a bombshell update on Christian McCaffrey that sets up Jordan Mason and Deebo Samuel for huge numbers the next few weeks.