NFL Week 11 Predictions, Picks, Props and Best Bets for Every Game

I had an unlucky week last week, but I've had a decent amount go in my favor throughout the course of the season, so I can't complain too much. Unfortunately I feel like Week 11 is probably one of the more difficult slates that I can recall this season, not just from a spread perspective, but just trying to pick moneylines as well.

Week 10 Record ATS: 5-9
Week 10 Record on Totals: 8-6

2025 Season Record ATS: 65-69
2025 Season Record on Totals: 73-62

NFL Week 11 Picks For Each Game

NFL Week 11 Predictions

In this article, we also take a look at NFL Week 11 odds and our predictions for each NFL game. Home teams are listed last.

Jets vs. Patriots

New England is obviously a much better team and there's very little reason to believe the Jets will be competent in any sort of capacity, but how often have we watched these primetime games just get gross enough where the bad team hangs around? It's such a foolish way to rationalize things, but this is a massive spread for a situation that we've repeatedly watched be a slop fest.

Spread Pick: Jets +12.5
Total Pick: Under 43.5

Commanders vs. Dolphins

I suppose at the start of the season this could have been a potentially interesting showcase game for the NFL internationally, but man has this devolved into something entirely different in the past month. I'll admit that I've been impressed by Miami's resolve following the firing of general manager Chris Grier as I thought the entire team was just looking forward to Cancun. I suppose Miami has just a bit of momentum in its favor compared to Washington's comical amount of injuries.

QUICK LINKS

Picks

See the best picks & player props

Sportsbook Promos

Get the Best Promos Available Today

Player Props

See the latest MLB Player Props

Spread Pick: Dolphins -2.5
Total Pick: Under 47.5

Panthers vs. Falcons

I hate this game so much because either team is liable to win or lose on any given week. There isn't any rhyme or reason as to why either team might be successful in that given week or come out flat. You'd like to assume the Falcons will play more inspired football after getting blown out by Carolina the last time around, but the Panthers also laid a complete egg against New Orleans the week before that I'd have to imagine could be a motivating factor. I don't even think this game is going to be particularly close, but I genuinely have no idea who will win.

Spread Pick: Panthers +3.5
Total Pick: Over 42.5

Buccaneers vs. Bills

Vegas is once again giving entirely too much credit to Buffalo. It'd be nice to see Tampa Bay get back some of its skill position guys to even the tides a bit, but I do think this team can still run against the Bills' defense even without Bucky Irving (shoulder/foot). I picked the Bills to finally win the Super Bowl this year and I don't think I'm quite ready to deviate from that proclamation, but this has not been the juggernaut team I thought they'd be this year.

Spread Pick: Buccaneers +5.5
Total Pick: Over 48.5

Chargers vs. Jaguars

I was very surprised to see Jackonsville as home dogs. I understand they haven't played well dating back to early October, but I think that has far more to do with the gauntlet of opponents they've faced (outside of the Raiders) than a team that has completely lost its way. Los Angeles is a good team. I think they will go further in the playoffs than Denver, for example. But it's the NFL, and West to East coast travel can be really difficult even if the Seahawks pretty thoroughly took care of business in similar recent situations.

Spread Pick: Jaguars +3
Total Pick: Over 43.5

Bears vs. Vikings

I think I've went back and forth on this game three times already at this point. I've been on record multiple times suggesting J.J. McCarthy is not a very good NFL quarterback right now. I don't think he'll ever get to that point, but especially this early into his career, I just don't trust that he's going to win any of these games against teams in similar status to Minnesota. But the Vikings do well play well at home, and they aren't incompetent in the way that they can't stay with teams either. I don't think Chicago's record reflects who they are as a team either, but I think they have an offense that generate points even in difficult situations, and there won't be any weather concerns obviously in the dome. If Minnesota was an underdog this would be a no brainer, but I think I'm just going to take the points and not think much harder about this.

Spread Pick: Bears +3
Total Pick: Under 48.5

Packers vs. Giants

This is about as easy money as it gets. A team without their head coach, QB1, RB1 and WR1 has been shockingly incredibly successful in Matt LaFleur's tenure as the head coach of the Packers. The Giants have also won each of the past two games against Green Bay, and one of those was with Tommy DeVito as the quarterback. I outright think the Giants win this game, but the total is just inconceivably wrong too for what should be at minimum one side scoring plenty of points.

Spread Pick: Giants +7
Total Pick: Over 43.5

Bengals vs. Steelers

This is yet another game that just seems unreasonable from a spread perspective. I think Pittsburgh is the better team and I believe they probably win, but unless Joe Flacco (shoulder) is just unavailable, I have to think Cincinnati can keep pace from a scoring perspective. This is a massive game for the AFC North and overall divisional games are always closer than you'd assume.

Spread Pick: Bengals +5.5
Total Pick: Under 48.5

Texans vs. Titans

I guess I'll zag at least on this one divisional game. I've been really impressed with Houston's offense really since the bye. We know the Texans have arguably the best defense in the league, which alone could beat the Titans on Sunday. But if C.J. Stroud (or Davis Mills given Stroud has not cleared concussion protocol) can utilize the sheer dearth of skill guys Houston amassed this offseason like we've seen of late, we're talking about Houston creeping ever closer to a balanced team overall.

Spread Pick: Texans -6.5
Total Pick: Under 37.5

49ers vs. Cardinals

San Francisco is obviously right up there in terms of most injuries throughout the entire year, but Arizona is quietly compiling plenty in recent weeks. I happen to think the Cardinals are the higher tier of the "good-bad teams", but this just seems like it would be a surprisingly loss for the 49ers.

Spread Pick: 49ers -3
Total Pick: Under 48.5

Seahawks vs. Rams

What a treat of a game. It's probably fair given the Thursday Night, Monday Night and European game are all incredibly dreadful, but this late afternoon Sunday slate is an absolute delight. I think the Rams win this one pretty convincingly, but I also feel relatively confident Seattle will do just fine in the Week 16 rematch. These are the two best teams in the NFC in my opinion, or maybe Detroit also gets to squeak into this conversation too. I guarantee whatever conversation happens after Sunday will be an overreaction.

Spread Pick: Rams -3
Total Pick: Over 48.5

Ravens vs. Browns

I think it's comical this game was a late afternoon one, but I had to think long and hard if Cleveland would cover. The Ravens have lost this type of game outright in past years, but I just don't think Dillon Gabriel is the type of quarterback to sustain the level of offense needed (two scores) in order for this spread to be in jeopardy.

Spread Pick: Ravens -7.5
Total Pick: Under 39.5

Chiefs vs. Broncos

I know a lot of people are wanting this game to be competitive, but I'd be very surprised if that happens. The Broncos just are not a good football team despite what their record indicates. Denver should not have won by a combined 16 points against the Jets, Giants, Texans, Titans and Raiders if we're supposed to assume they're some sort of juggernaut. Good on the Broncos for winning the games on their schedule, but a contending team that does not make. We're not going to really know much about the Broncos entering the posteason either as they effectively only have three tough games (another against the Chiefs and Chargers, and a Week 16 against the dumb Packers in Denver) the rest of the way.

Spread Pick: Chiefs -3.5
Total Pick: Over 43.5

Lions vs. Eagles

This should be another excellent game. Philadelphia should take advantage of a meager Detroit secondary, but they're completely unwilling to pass the ball right now. If we're going to see a repeat of the Eagles' offense from last Monday against the Lions this week, I don't anticpate this game will be all that close. And frankly, outside of maybe 2.5 games this season, that Monday win over the Packers is who Philadelphia has been all season. I don't expect that to change magically just because they're facing a better opponent.

Spread Pick: Lions +2.5
Total Pick: Under 46.5

Cowboys vs. Raiders

I desperately hope the schedule makers do better next year. There is absolutely zero reason why we ever need to see the Raiders on primetime unless it's like a Week 16 Thursday Night football game. Obviously the Cowboys will win, and I truthfully don't care by how much. I'm just ready to get to the portion of the season where we can forget Las Vegas is even a franchise. We're only a few more weeks away from that blissful place.

Spread Pick: Cowboys -3.5
Total Pick: Under 50.5

NFL Week 11 Best Bets

Next, we take a look at our favorite Week 11 NFL best bets at the best NFL betting sites. Outside of correctly guessing how NO/CAR would go, it was a pretty subpar week. I'll be entirely truthful that I don't have any degree of confidence in this week's slate, much less the props. Maybe that would make for a good teaser week, but arguably there's very few best bets that I'm comfortable recommending.

BetMGM Best Bets for NFL Week 11

BetMGM offers some of the best odds available for Week 11. If you're not signed up at BetMGM yet, new players at BetMGM can use the BetMGM bonus code ROTOBONUS for a risk-free bet worth up to $1,000. Here are our NFL best bets for Week 11 at BetMGM.

• 49ers moneyline (-155)
• Ravens first-half moneyline (-275)

Caesars Sportsbook Best Bets for NFL Week 11

Caesars Sportsbook also has great betting odds for NFL Week 11. If you are not registered yet, use the Caesars Sportsbook promo code ROTOFULL for a first bet on Caesars.

• Two-team 6.5-point teaser (-140) - Ravens -1/Bengals +12

DraftKings Best Bets for NFL Week 11

The DraftKings Sportsbook has special offers for new users just in time for Week 11 of the NFL season. Here are our best picks available at the DraftKings Sportsbook this week.

• Giants moneyline (+295)
• Rams -3 (-105)

FanDuel Best Bets for NFL Week 11

One of the most popular sportsbooks available is FanDuel Sportsbook. Let's take a look at our favorite betting picks with FanDuel odds.

• Three-item moneyline (+246) - Rams, 49ers and Texans to win
  • You could probably wait a bit later to confirm C.J. Stroud (concussion) won't play, but I'd still pick Texans

BetRivers Best Bets for NFL Week 11

BetRivers is an up-and-coming and underrated sportsbook, and they are offering up to $500 in second-chance bets with the BetRivers bonus code. Bettors can use those for these picks on NFL Week 11.

• Either team to score a defense or special teams TD in NYJ/NE (+350)
• Lions +2.5 (-105)

Fanatics Sportsbook Best Bets for NFL Week 11

For bettors looking for a unique way to wager, try the Fanatics Sportsbook promo code for our Week 11 NFL picks.

• Bears +2.5 (+100)
• Cowboys -3.5 (-105)

Look ahead at the NFL Week 12 odds as well, if you're interested in getting ahead of the line movement.