There are huge implications for both Roma and Inter on Sunday, and RotoWire's Juan Pablo Aravena is expecting Lautaro Martinez to have a big impact on the match.
Chile can clinch the top spot in Group C with just a draw Monday, but Uruguay come in favored to win the clash of titans.
Lionel Messi has been nearly unstoppable this season, but he'll face a tough task Saturday against Atletico Madrid.
Atletico Madrid continue to fight for the top of La Liga, and they'll need a solid performance from Antoine Griezmann on Saturday against Alaves.
Cristiano Ronaldo's price is higher than anyone else, but RotoWire's Adam Zdroik explains why it'll be tough to avoid the Juventus star on Tuesday.
Tottenham need a win against Barcelona at the Camp Nou on Tuesday, and if they are going to pull it off, Christian Eriksen is likely to play a big part.
Friday's two-game slate includes a number of high-profile stars, and while he's the most expensive player on FanDuel, Neymar will be very hard to fade.
FanDuel is offering three sizable slates for Monday's four World Cup matches, with fantasy players having to decide whether or not to pay up for Cristiano Ronaldo and/or Mohamed Salah.
The final round of group stage matches kick off Monday, With Spain and Portugal still looking to lock up their spots in the round of 16.
It's going to be very tough fitting in attackers from Uruguay and Spain on Wednesday's two-game slate, but Chris Owen has a few value plays who could help out.
Mohamed Salah's potential return from injury leaves a lot of questions for tomorrow's three-game slate, but the Uruguay attackers still come in with the best upsides based on matchup.
Mohamed Salah looks ready to return from his shoulder injury, but is he worth playing against Uruguay? RotoWire's Andrew Laird breaks down the three-game slate.
Uruguay are significant favorites to win Group A, but the bigger story line will be whether Russia can avoid being just the second host nation to not reach the knockout rounds.
Manchester United are heavily favored over FC Basel on Tuesday, and fantasy owners could get plenty of points out of midfielder Henrik Mkhitaryan.
Radamel Falcao has resurrected his career with Monaco this season, and he could be a key piece if they are to upset Manchester City in England on Tuesday.
Lionel Messi comes in as the most expensive player on the slate, but Alex Spalding has just the right players to pair with the Barcelona superstar without struggling with salary cap space.
Cristiano Ronaldo looks poised to return from injury as he will try to get Real Madrid into the Champions League final after a scoreless first leg against Manchester City.