Justin Jefferson looks truly unstoppable in a game where the Vikings need points and the Lions probably can't cover.
Michael Penix is unproven, but the quarterback change gives new hope to Falcons pass catchers like Drake London.
Ever since Marshon Lattimore switched teams, Washington's Week 15 matchup with New Orleans became a good matchup for Terry McLaurin.
Terry McLaurin should stay hot against a Titans defense starting its third- and fourth-string corners on the boundary.
The Ravens might want to shadow George Pickens with Marlon Humphrey, because the other Ravens corners can't cover Pickens.
Deebo Samuel could go nuts as the desperate 49ers take aim at a weak Tampa Bay corner rotation.
With Tua Tagovailoa back in the lineup Jaylen Waddle should get rolling against Arizona, and the same is true of Tyreek Hill if he plays through his foot injury.
The showdown between Detroit and Dallas could set up a punch-for-punch heavyweight contest where CeeDee Lamb and Amon-Ra St. Brown both go off.
Michael Pittman got back on track in Week 4 and should keep it rolling in Week 5, as neither the Jags nor Colts have viable coverage personnel.
Jakobi Meyers and Brock Bowers should see a lot of targets with Davante Adams and Michael Mayer ruled out. RW's Jerry Donabedian breaks down all the other big injury news and fantasy implications from Friday.
George Pickens should get going against an Indianapolis defense with questionable boundary personnel
Cole Kmet pushed Gerald Everett aside after sharing snaps for the first two weeks of the season. RW's Jerry Donabedian assesses that and much more in his recap of Week 3 action.
If Patrick Surtain shadows Mike Evans on the boundary then it could create a target funnel to Chris Godwin in the slot.
The Jaguars locked in franchise QB Trevor Lawrence to a long-term deal this offseason, ensuring he'll be around for years to come. In the short term, though, he'll be looking to bounce back from an uneven 2023.