Justin Jefferson looks truly unstoppable in a game where the Vikings need points and the Lions probably can't cover.
In the IDP Fallers category, E.J. Speed tallied only five tackles against the Giants Week 18 after a one-game absence.
Drake London's breakout should continue against a Seattle secondary that might be without its two starting boundary corners.
The showdown between Detroit and Dallas could set up a punch-for-punch heavyweight contest where CeeDee Lamb and Amon-Ra St. Brown both go off.
Michael Pittman got back on track in Week 4 and should keep it rolling in Week 5, as neither the Jags nor Colts have viable coverage personnel.
George Pickens should get going against an Indianapolis defense with questionable boundary personnel
If Patrick Surtain shadows Mike Evans on the boundary then it could create a target funnel to Chris Godwin in the slot.
If New England prioritizes defending Travis Kelce then the Pats might not have leftover personnel to cover Rashee Rice.
Rhamondre Stevenson is the centerpiece of a broken offense, and this should be one of his better weeks thanks to Sunday's matchup with another last-place team.