Justin Jefferson looks truly unstoppable in a game where the Vikings need points and the Lions probably can't cover.
Michael Penix is unproven, but the quarterback change gives new hope to Falcons pass catchers like Drake London.
There's a chance DJ Moore maintains his momentum against a Detroit secondary without Carlton Davis on Thursday.
Drake London's breakout should continue against a Seattle secondary that might be without its two starting boundary corners.
Facing a tough defense with the bull's eye on him, Sunday's showdown with Buffalo will help clarify just how good Rashee Rice can be.
Terry McLaurin should stay hot in an indoor game against a Houston defense that lacks speed.
Xavien Howard is more of a ballhawk than a shutdown corner, so Amari Cooper should do well in the warm weather Sunday.
With better coverage in the seam than the perimeter, expect Mike Evans to hit the ground running against the Chiefs.
Mario Puig analyzes the wide receiver-cornerback matchups for Week 3. Allen Robinson is poised to finally break out after a slow two-week start to his Rams career.
Aaron Jones didn't get enough work in Week 1, and the Packers know that's a losing formula.
Mitch Trubisky can miss the wide side of a barn, but Chase Claypool could do damage anyway against New England's tiny and slow slot corner.
Jaire Alexander might be able to contain Justin Jefferson, but the Packers might not have the luxury of matching them up.
Russell Gage's hot streak should continue against Detroit's battered secondary.
The spotlight is on Michael Gallup as the Dallas offense tries to operate potentially without CeeDee Lamb and Amari Cooper.
Jamison Crowder could be busy running against the interior of Miami's defense, away from Xavien Howard and Byron Jones.
It's been an up-and-down season for the Philly passing game, but DeVonta Smith should swing back upward against Detroit.
The big play should show up soon for Jaylen Waddle -- perhaps Sunday against Atlanta's backup slot CB.
It's been a disappointing year for Allen Robinson, but in Week 6 he faces a battered and reeling Green Bay secondary.